Targeted inhibition of the COP9 signalosome for treatment of cancer

by Anita Schlierf, Eva Altmann, Jean Quancard, Anne B. Jefferson, René Assenberg, Martin Renatus, Matthew Jones, Ulrich Hassiepen, Michael Schaefer, Michael Kiffe, Andreas Weiss, Christian Wiesmann, Richard Sedrani, Jörg Eder, Bruno Martoglio
Published 2016-10-01

Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism.

by Marc Bigaud, Zuhal Dincer, Birgit Bollbuck, Janet Dawson, Nicolau Beckmann, Christian Beerli, Gina Fishli-Cavelti, Michaela Nahler, Daniela Angst, Philipp Janser, Heike Otto, Elisabeth Rosner, Rene Hersperger, Christian Bruns, Jean Quancard
Published 2016-01-01

Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology

by Kea Martin, Ursula Junker, Elaine Tritto, Esther Sutter, Tina Rubic-Schneider, Hannah Morgan, Satoru Niwa, Jianping Li, Achim Schlapbach, Dana Walker, Marc Bigaud, Christian Beerli, Amanda Littlewood-Evans, Bettina Rudolph, Marc Laisney, David Ledieu, Karen Beltz, Jean Quancard, Frédéric Bornancin, Natasa Zamurovic Ribrioux, Thomas Calzascia
Published 2020-04-01