Xenogeneic human p53 DNA vaccination by electroporation breaks immune tolerance to control murine tumors expressing mouse p53.

by Ruey-Shyang Soong, Janson Trieu, Sung Yong Lee, Liangmei He, Ya-Chea Tsai, T-C Wu, Chien-Fu Hung
Published 2013-01-01

Direct T cell activation via CD40 ligand generates high avidity CD8+ T cells capable of breaking immunological tolerance for the control of tumors.

by Ruey-Shyang Soong, Liwen Song, Janson Trieu, Sung Yong Lee, Liangmei He, Ya-Chea Tsai, T-C Wu, Chien-Fu Hung
Published 2014-01-01