Unfractionated and Low Molecular Weight Heparin Reduce Platelet Induced Epithelial-Mesenchymal Transition in Pancreatic and Prostate Cancer Cells

by Jan Moritz Ponert, Lukas Maria Gockel, Svenja Henze, Martin Schlesinger
Published 2018-10-01

The Low Molecular Weight Heparin Tinzaparin Attenuates Platelet Activation in Terms of Metastatic Niche Formation by Coagulation-Dependent and Independent Pathways

by Lukas Maria Gockel, Jan Moritz Ponert, Svenja Schwarz, Martin Schlesinger, Gerd Bendas
Published 2018-10-01

The mechanisms how heparin affects the tumor cell induced VEGF and chemokine release from platelets to attenuate the early metastatic niche formation.

by Jan Moritz Ponert, Svenja Schwarz, Reza Haschemi, Jens Müller, Bernd Pötzsch, Gerd Bendas, Martin Schlesinger
Published 2018-01-01