Multi-host expression system for recombinant production of challenging proteins.

by Steffen Meyer, Carmen Lorenz, Bahar Baser, Mona Wördehoff, Volker Jäger, Joop van den Heuvel
Published 2013-01-01

Identifying parameters to improve the reproducibility of transient gene expression in High Five cells.

by Maren Bleckmann, Margitta Schürig, Michelle Endres, Anke Samuels, Daniela Gebauer, Nadine Konisch, Joop van den Heuvel
Published 2019-01-01

Production of Recombinant Vaccine Cb Peritrophin-42 of Screwworm Fly in Escherichia coli and Saccharomyces cerevisiae

by DESSY NATALIA, SRI MUHARSINI, FIFI FITRIAH MASDUKI, APRIL HARI WARDHANA, SAVIRA EKA WARDANI, ELIZABETH MARIA, JOOP VAN DEN HEUVEL
Published 2010-03-01

Identification of Essential Genetic Baculoviral Elements for Recombinant Protein Expression by Transactivation in Sf21 Insect Cells.

by Maren Bleckmann, Margitta Schürig, Fang-Fang Chen, Zen-Zen Yen, Nils Lindemann, Steffen Meyer, Johannes Spehr, Joop van den Heuvel
Published 2016-01-01

Genomic Analysis and Isolation of RNA Polymerase II Dependent Promoters from Spodoptera frugiperda.

by Maren Bleckmann, Markus H-Y Fritz, Sabin Bhuju, Michael Jarek, Margitta Schürig, Robert Geffers, Vladimir Benes, Hüseyin Besir, Joop van den Heuvel
Published 2015-01-01

ER intrabody-mediated inhibition of interferon α secretion by mouse macrophages and dendritic cells.

by Konrad Büssow, Philipp Themann, Sabine Luu, Paul Pentrowski, Claudia Harting, Mira Majewski, Veith Vollmer, Mario Köster, Martina Grashoff, Rainer Zawatzky, Joop Van den Heuvel, Andrea Kröger, Thomas Böldicke
Published 2019-01-01

Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.

by Sonja Wilke, Lothar Groebe, Vitali Maffenbeier, Volker Jäger, Manfred Gossen, Jörn Josewski, Agathe Duda, Lilia Polle, Raymond J Owens, Dagmar Wirth, Dirk W Heinz, Joop van den Heuvel, Konrad Büssow
Published 2011-01-01

Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.

by Yazh Muthukumar, Johanna Münkemer, Daniel Mathieu, Christian Richter, Harald Schwalbe, Heinrich Steinmetz, Wolfgang Kessler, Joachim Reichelt, Ulrike Beutling, Ronald Frank, Konrad Büssow, Joop van den Heuvel, Mark Brönstrup, Richard E Taylor, Sabine Laschat, Florenz Sasse
Published 2018-01-01

Baculovirus-free insect cell expression system for high yield antibody and antigen production

by Janin Korn, Dorina Schäckermann, Toni Kirmann, Federico Bertoglio, Stephan Steinke, Janyn Heisig, Maximilian Ruschig, Gertrudis Rojas, Nora Langreder, Esther Veronika Wenzel, Kristian Daniel Ralph Roth, Marlies Becker, Doris Meier, Joop van den Heuvel, Michael Hust, Stefan Dübel, Maren Schubert
Published 2020-12-01

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

by Danielle M. DiCara, Dimitri Y. Chirgadze, Anthony R. Pope, Aneesh Karatt-Vellatt, Anja Winter, Peter Slavny, Joop van den Heuvel, Kothai Parthiban, Jane Holland, Len C. Packman, Georgia Mavria, Jens Hoffmann, Walter Birchmeier, Ermanno Gherardi, John McCafferty
Published 2017-08-01

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

by Federico Bertoglio, Viola Fühner, Maximilian Ruschig, Philip Alexander Heine, Leila Abassi, Thomas Klünemann, Ulfert Rand, Doris Meier, Nora Langreder, Stephan Steinke, Rico Ballmann, Kai-Thomas Schneider, Kristian Daniel Ralph Roth, Philipp Kuhn, Peggy Riese, Dorina Schäckermann, Janin Korn, Allan Koch, M. Zeeshan Chaudhry, Kathrin Eschke, Yeonsu Kim, Susanne Zock-Emmenthal, Marlies Becker, Margitta Scholz, Gustavo Marçal Schmidt Garcia Moreira, Esther Veronika Wenzel, Giulio Russo, Hendrikus S.P. Garritsen, Sebastian Casu, Andreas Gerstner, Günter Roth, Julia Adler, Jakob Trimpert, Andreas Hermann, Thomas Schirrmann, Stefan Dübel, André Frenzel, Joop Van den Heuvel, Luka Čičin-Šain, Maren Schubert, Michael Hust
Published 2021-07-01