MET gene copy number predicts worse overall survival in patients with non-small cell lung cancer (NSCLC); a systematic review and meta-analysis.

by Anastasios Dimou, Lemuel Non, Young Kwang Chae, William J Tester, Konstantinos N Syrigos
Published 2014-01-01

Borehole research in New York State can advance utilization of low-enthalpy geothermal energy, management of potential risks, and understanding of deep sedimentary and crystalline...

by T. Jordan, P. Fulton, J. Tester, D. Bruhn, H. Asanuma, U. Harms, C. Wang, D. Schmitt, P. J. Vardon, H. Hofmann, T. Pasquini, J. Smith
Published 2020-12-01

Arrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Intracellular Acidosis.

by Rou-Mu Hu, Bi-Hua Tan, David J Tester, Chunhua Song, Yang He, Sinisa Dovat, Blaise Z Peterson, Michael J Ackerman, Jonathan C Makielski
Published 2015-01-01

Even pore-localizing missense variants at highly conserved sites in KCNQ1-encoded Kv7.1 channels may have wild-type function and not cause type 1 long QT syndrome: Do not rely sole...

by Ashley Paquin, BA, Dan Ye, MD, David J. Tester, BS, Jamie D. Kapplinger, BA, Michael T. Zimmermann, PhD, Michael J. Ackerman, MD, PhD
Published 2018-02-01

LQTS-associated mutation A257G in α1-syntrophin interacts with the intragenic variant P74L to modify its biophysical phenotype

by Michael J. Ackerman, David J. Tester, Carmen R. Valdivia, Bi-Hua Tan, Jonathan C. Makielski, Matteo Vatta, Argelia Medeiros-Domingo, Jianding Cheng, David W. Van Norstrand
Published 2011-08-01

A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis.

by Jessica A Hennessey, Nicole J Boczek, Yong-Hui Jiang, Joelle D Miller, William Patrick, Ryan Pfeiffer, Brittan S Sutphin, David J Tester, Hector Barajas-Martinez, Michael J Ackerman, Charles Antzelevitch, Ronald Kanter, Geoffrey S Pitt
Published 2014-01-01