Therapeutic Targeting of Notch Signaling: From Cancer to Inflammatory Disorders

by Frederick Allen, Frederick Allen, Ivan Maillard, Ivan Maillard
Published 2021-05-01

Notch signalling in T cell homeostasis and differentiation

by Joshua D. Brandstadter, Ivan Maillard
Published 2019-11-01

The PAF1c Subunit CDC73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays Leukemia-Specific Gene Regulation

by Nirmalya Saha, James Ropa, Lili Chen, Hsiangyu Hu, Maria Mysliwski, Ann Friedman, Ivan Maillard, Andrew G. Muntean
Published 2019-05-01

Increased expression of PcG protein YY1 negatively regulates B cell development while allowing accumulation of myeloid cells and LT-HSC cells.

by Xuan Pan, Morgan Jones, Jie Jiang, Kristina Zaprazna, Duonan Yu, Warren Pear, Ivan Maillard, Michael L Atchison
Published 2012-01-01

Elucidating the Importance of DOT1L Recruitment in MLL-AF9 Leukemia and Hematopoiesis

by Sierrah M. Grigsby, Ann Friedman, Jennifer Chase, Bridget Waas, James Ropa, Justin Serio, Chenxi Shen, Andrew G. Muntean, Ivan Maillard, Zaneta Nikolovska-Coleska
Published 2021-02-01

Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.

by Jon C Aster, Nick Bodnar, Lanwei Xu, Fredrick Karnell, John M Milholland, Ivan Maillard, Gavin Histen, Yunsun Nam, Stephen C Blacklow, Warren S Pear
Published 2011-01-01

TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis

by Sherilyn Grill, Shilpa Padmanaban, Ann Friedman, Eric Perkey, Frederick Allen, Valerie M. Tesmer, Jennifer Chase, Rami Khoriaty, Catherine E. Keegan, Ivan Maillard, Jayakrishnan Nandakumar
Published 2021-05-01

Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing

by Andrew S. Kimball, Amrita D. Joshi, Anna E. Boniakowski, Matthew Schaller, Jooho Chung, Ronald Allen, Jennifer Bermick, William F. Carson, Peter K. Henke, Ivan Maillard, Steve L. Kunkel, Katherine A. Gallagher
Published 2017-06-01

Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

by Juana Serrano-Lopez, Shailaja Hegde, Sachin Kumar, Josefina Serrano, Jing Fang, Ashley M Wellendorf, Paul A Roche, Yamileth Rangel, Leolene J Carrington, Hartmut Geiger, H Leighton Grimes, Sanjiv Luther, Ivan Maillard, Joaquin Sanchez-Garcia, Daniel T Starczynowski, Jose A Cancelas
Published 2021-04-01

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

by David S. Rogawski, Jing Deng, Hao Li, Hongzhi Miao, Dmitry Borkin, Trupta Purohit, Jiho Song, Jennifer Chase, Shuangjiang Li, Juliano Ndoj, Szymon Klossowski, EunGi Kim, Fengbiao Mao, Bo Zhou, James Ropa, Marta Z. Krotoska, Zhuang Jin, Patricia Ernst, Xiaomin Feng, Gang Huang, Kenichi Nishioka, Samantha Kelly, Miao He, Bo Wen, Duxin Sun, Andrew Muntean, Yali Dou, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka
Published 2021-05-01