Directed evolution of P-glycoprotein cysteines reveals site-specific, non-conservative substitutions that preserve multidrug resistance

by Douglas J. Swartz, Leo Mok, Sri K. Botta, Anukriti Singh, Guillermo A. Altenberg, Ina L. Urbatsch
Published 2014-06-01

A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastoris.

by Jiangping Bai, Douglas J Swartz, Irina I Protasevich, Christie G Brouillette, Patina M Harrell, Ellen Hildebrandt, Brigitte Gasser, Diethard Mattanovich, Andrew Ward, Geoffrey Chang, Ina L Urbatsch
Published 2011-01-01