Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms

by Yan Zhang, Maria H. Ulvmar, Lukas Stanczuk, Ines Martinez-Corral, Maike Frye, Kari Alitalo, Taija Mäkinen
Published 2018-04-01

Lymph Node Transplantation Decreases Swelling and Restores Immune Responses in a Transgenic Model of Lymphedema.

by Jung-Ju Huang, Jason C Gardenier, Geoffrey E Hespe, Gabriela D García Nores, Raghu P Kataru, Catherine L Ly, Inés Martínez-Corral, Sagrario Ortega, Babak J Mehrara
Published 2016-01-01

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

by Lukas Stanczuk, Ines Martinez-Corral, Maria H. Ulvmar, Yang Zhang, Bàrbara Laviña, Marcus Fruttiger, Ralf H. Adams, Dieter Saur, Christer Betsholtz, Sagrario Ortega, Kari Alitalo, Mariona Graupera, Taija Mäkinen
Published 2015-03-01

Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation

by Ines Martinez-Corral, Yan Zhang, Milena Petkova, Henrik Ortsäter, Sofie Sjöberg, Sandra D. Castillo, Pascal Brouillard, Louis Libbrecht, Dieter Saur, Mariona Graupera, Kari Alitalo, Laurence Boon, Miikka Vikkula, Taija Mäkinen
Published 2020-06-01

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program

by Maike Frye, Andrea Taddei, Cathrin Dierkes, Ines Martinez-Corral, Matthew Fielden, Henrik Ortsäter, Jan Kazenwadel, Dinis P. Calado, Pia Ostergaard, Marjo Salminen, Liqun He, Natasha L. Harvey, Friedemann Kiefer, Taija Mäkinen
Published 2018-04-01

PROX1 is a transcriptional regulator of MMP14

by Silvia Gramolelli, Jianpin Cheng, Ines Martinez-Corral, Markus Vähä-Koskela, Endrit Elbasani, Elisa Kaivanto, Ville Rantanen, Krista Tuohinto, Sampsa Hautaniemi, Mark Bower, Caj Haglund, Kari Alitalo, Taija Mäkinen, Tatiana V. Petrova, Kaisa Lehti, Päivi M. Ojala
Published 2018-06-01