The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

by Johanna Roostalu, Claire Thomas, Nicholas Ian Cade, Simone Kunzelmann, Ian A Taylor, Thomas Surrey
Published 2020-02-01

The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS.

by Robert Yan, Martin Friemel, Claudia Aloisi, Martijn Huynen, Ian A Taylor, Silke Leimkühler, Annalisa Pastore
Published 2016-01-01

Novel escape mutants suggest an extensive TRIM5α binding site spanning the entire outer surface of the murine leukemia virus capsid protein.

by Sadayuki Ohkura, David C Goldstone, Melvyn W Yap, Kate Holden-Dye, Ian A Taylor, Jonathan P Stoye
Published 2011-03-01

Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis

by Elizabeth R. Morris, Sarah J. Caswell, Simone Kunzelmann, Laurence H. Arnold, Andrew G. Purkiss, Geoff Kelly, Ian A. Taylor
Published 2020-06-01

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

by Matthew A. Cottee, Sean L. Beckwith, Suzanne C. Letham, Sarah J. Kim, George R. Young, Jonathan P. Stoye, David J. Garfinkel, Ian A. Taylor
Published 2021-09-01

FAN1 Activity on Asymmetric Repair Intermediates Is Mediated by an Atypical Monomeric Virus-type Replication-Repair Nuclease Domain

by Simon Pennell, Anne-Cécile Déclais, Jiejin Li, Lesley F. Haire, Wioletta Berg, José W. Saldanha, Ian A. Taylor, John Rouse, David M.J. Lilley, Stephen J. Smerdon
Published 2014-07-01

A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets

by Fruzsina Hobor, Andre Dallmann, Neil J. Ball, Carla Cicchini, Cecilia Battistelli, Roksana W. Ogrodowicz, Evangelos Christodoulou, Stephen R. Martin, Alfredo Castello, Marco Tripodi, Ian A. Taylor, Andres Ramos
Published 2018-02-01

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.

by Sofia Banchenko, Ferdinand Krupp, Christine Gotthold, Jörg Bürger, Andrea Graziadei, Francis J O'Reilly, Ludwig Sinn, Olga Ruda, Juri Rappsilber, Christian M T Spahn, Thorsten Mielke, Ian A Taylor, David Schwefel
Published 2021-08-01

Structural basis for Fullerene geometry in a human endogenous retrovirus capsid

by Oliver Acton, Tim Grant, Giuseppe Nicastro, Neil J. Ball, David C. Goldstone, Laura E. Robertson, Kasim Sader, Andrea Nans, Andres Ramos, Jonathan P. Stoye, Ian A. Taylor, Peter B. Rosenthal
Published 2019-12-01

A unique spumavirus Gag N-terminal domain with functional properties of orthoretroviral matrix and capsid.

by David C Goldstone, Thomas G Flower, Neil J Ball, Marta Sanz-Ramos, Melvyn W Yap, Roksana W Ogrodowicz, Nicole Stanke, Juliane Reh, Dirk Lindemann, Jonathan P Stoye, Ian A Taylor
Published 2013-05-01

Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.

by Neil J Ball, Giuseppe Nicastro, Moumita Dutta, Dominic J Pollard, David C Goldstone, Marta Sanz-Ramos, Andres Ramos, Erik Müllers, Kristin Stirnnagel, Nicole Stanke, Dirk Lindemann, Jonathan P Stoye, William R Taylor, Peter B Rosenthal, Ian A Taylor
Published 2016-11-01

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.

by Laurence H Arnold, Harriet C T Groom, Simone Kunzelmann, David Schwefel, Sarah J Caswell, Paula Ordonez, Melanie C Mann, Sabrina Rueschenbaum, David C Goldstone, Simon Pennell, Steven A Howell, Jonathan P Stoye, Michelle Webb, Ian A Taylor, Kate N Bishop
Published 2015-10-01