Discovery of 5-methyl-N-(2-arylquinazolin-7-yl)isoxazole-4-carboxamide analogues as highly selective FLT3 inhibitors

by Daseul Im, Hyungwoo Moon, Jinwoong Kim, Youri Oh, Miyoung Jang, Jung-Mi Hah
Published 2020-01-01

Conformational restriction of a type II FMS inhibitor leading to discovery of 5-methyl-N-(2-aryl-1H-benzo[d]imidazo-5-yl)isoxazole-4-carboxamide analogues as selective FLT3 inhibit...

by Daseul Im, Hyungwoo Moon, Jingwoong Kim, Youri Oh, Miyoung Jang, Jung-Mi Hah
Published 2019-01-01

Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives as a novel selective inhibitor scaffold of JNK3

by Youri Oh, Miyoung Jang, Hyunwook Cho, Songyi Yang, Daseul Im, Hyungwoo Moon, Jung-Mi Hah
Published 2020-01-01

Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitor

by Jinwoong Kim, Byeongha Choi, Daseul Im, Hoyong Jung, Hyungwoo Moon, Waqar Aman, Jung-Mi Hah
Published 2019-01-01

Discovery of 1-Pyrimidinyl-2-Aryl-4,6-Dihydropyrrolo [3,4-d]Imidazole-5(1<i>H</i>)-Carboxamide as a Novel JNK Inhibitor

by Miyoung Jang, Youri Oh, Hyunwook Cho, Songyi Yang, Hyungwoo Moon, Daseul Im, Jung-Mi Hah
Published 2020-03-01