Cancer Therapy by Catechins Involves Redox Cycling of Copper Ions and Generation of Reactive Oxygen Species

by Mohd Farhan, Husain Yar Khan, Mohammad Oves, Ahmed Al-Harrasi, Nida Rehmani, Hussain Arif, Sheikh Mumtaz Hadi, Aamir Ahmad
Published 2016-02-01

Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism

by Haseeb Zubair, Shafquat Azim, Husain Yar Khan, Mohammad Fahad Ullah, Daocheng Wu, Ajay Pratap Singh, Sheikh Mumtaz Hadi, Aamir Ahmad
Published 2016-06-01

Antiproliferative and Carbonic Anhydrase II Inhibitory Potential of Chemical Constituents from <i>Lycium shawii</i> and <i>Aloe vera</i>: Evidence from In Silico Target Fishing and...

by Najeeb Ur Rehman, Sobia Ahsan Halim, Majid Khan, Hidayat Hussain, Husain Yar Khan, Ajmal Khan, Ghulam Abbas, Kashif Rafiq, Ahmed Al-Harrasi
Published 2020-05-01

Nuclear Export Inhibitor KPT-8602 Synergizes with PARP Inhibitors in Escalating Apoptosis in Castration Resistant Cancer Cells

by Md. Hafiz Uddin, Yiwei Li, Husain Yar Khan, Irfana Muqbil, Amro Aboukameel, Rachel E. Sexton, Shriya Reddy, Yosef Landesman, Trinayan Kashyap, Asfar S. Azmi, Elisabeth I. Heath
Published 2021-06-01

Targeting XPO1 and PAK4 in 8505C Anaplastic Thyroid Cancer Cells: Putative Implications for Overcoming Lenvatinib Therapy Resistance

by Husain Yar Khan, James Ge, Misako Nagasaka, Amro Aboukameel, Gabriel Mpilla, Irfana Muqbil, Mark Szlaczky, Mahmoud Chaker, Erkan Baloglu, Yosef Landesman, Ramzi M. Mohammad, Asfar S. Azmi, Ammar Sukari
Published 2019-12-01

Calcium Release-Activated Calcium (CRAC) Channel Inhibition Suppresses Pancreatic Ductal Adenocarcinoma Cell Proliferation and Patient-Derived Tumor Growth

by Husain Yar Khan, Gabriel B. Mpilla, Rachel Sexton, Srikant Viswanadha, Kumar V. Penmetsa, Amro Aboukameel, Maria Diab, Mandana Kamgar, Mohammed Najeeb Al-Hallak, Mark Szlaczky, Anteneh Tesfaye, Steve Kim, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi
Published 2020-03-01