Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations

by Huaibin Chen, Zhifeng Huang, Kaushik Dutta, Steven Blais, Thomas A. Neubert, Xiaokun Li, David Cowburn, Nathaniel J. Traaseth, Moosa Mohammadi
Published 2013-07-01

The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors

by Sara A Byron, Huaibin Chen, Andreas Wortmann, David Loch, Michael G Gartside, Farhad Dehkhoda, Steven P Blais, Thomas A Neubert, Moosa Mohammadi, Pamela M Pollock
Published 2013-08-01

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

by Huaibin Chen, William M Marsiglia, Min-Kyu Cho, Zhifeng Huang, Jingjing Deng, Steven P Blais, Weiming Gai, Shibani Bhattacharya, Thomas A Neubert, Nathaniel J Traaseth, Moosa Mohammadi
Published 2017-02-01