The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria.

by Heleen Van Acker, Jan Gielis, Marloes Acke, Freya Cools, Paul Cos, Tom Coenye
Published 2016-01-01

Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms.

by Lisa Slachmuylders, Heleen Van Acker, Gilles Brackman, Andrea Sass, Filip Van Nieuwerburgh, Tom Coenye
Published 2018-01-01

Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggest...

by Claudia Udine, Gilles Brackman, Silvia Bazzini, Silvia Buroni, Heleen Van Acker, Maria Rosalia Pasca, Giovanna Riccardi, Tom Coenye
Published 2013-01-01

Coumarin Reduces Virulence and Biofilm Formation in Pseudomonas aeruginosa by Affecting Quorum Sensing, Type III Secretion and C-di-GMP Levels

by Yunhui Zhang, Andrea Sass, Heleen Van Acker, Jasper Wille, Bruno Verhasselt, Filip Van Nieuwerburgh, Volkhard Kaever, Aurélie Crabbé, Tom Coenye
Published 2018-08-01

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics.

by Aurélie Crabbé, Lisa Ostyn, Sorien Staelens, Charlotte Rigauts, Martijn Risseeuw, Maarten Dhaenens, Simon Daled, Heleen Van Acker, Dieter Deforce, Serge Van Calenbergh, Tom Coenye
Published 2019-04-01

Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species.

by Heleen Van Acker, Andrea Sass, Silvia Bazzini, Karen De Roy, Claudia Udine, Thomas Messiaen, Giovanna Riccardi, Nico Boon, Hans J Nelis, Eshwar Mahenthiralingam, Tom Coenye
Published 2013-01-01

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

by Eline Teirlinck, Ranhua Xiong, Toon Brans, Katrien Forier, Juan Fraire, Heleen Van Acker, Nele Matthijs, Riet De Rycke, Stefaan C. De Smedt, Tom Coenye, Kevin Braeckmans
Published 2018-10-01

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth

by Heleen Van Acker, Aurélie Crabbé, Dukas Jurėnas, Lisa Ostyn, Andrea Sass, Simon Daled, Maarten Dhaenens, Dieter Deforce, Eline Teirlinck, Herlinde De Keersmaecker, Kevin Braeckmans, Laurence Van Melderen, Tom Coenye
Published 2019-12-01