Antiplasmodial and Cytotoxic Flavonoids from <i>Pappea capensis</i> (Eckl. & Zeyh.) Leaves

by Nasir Tajuddeen, Tarryn Swart, Heinrich C. Hoppe, Fanie R. van Heerden
Published 2021-06-01

Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays

by Magambo Phillip Kimuda, Dustin Laming, Heinrich C. Hoppe, Özlem Tastan Bishop
Published 2019-01-01

Potential repurposing of four FDA approved compounds with antiplasmodial activity identified through proteome scale computational drug discovery and in vitro assay

by Bakary N’tji Diallo, Tarryn Swart, Heinrich C. Hoppe, Özlem Tastan Bishop, Kevin Lobb
Published 2021-01-01

Genomes2Drugs: identifies target proteins and lead drugs from proteome data.

by David Toomey, Heinrich C Hoppe, Marian P Brennan, Kevin B Nolan, Anthony J Chubb
Published 2009-07-01

Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones

by Richard M. Beteck, Lesetja J. Legoabe, Michelle Isaacs, Setshaba D. Khanye, Dustin Laming, Heinrich C. Hoppe
Published 2019-05-01

Easy-to-Access Quinolone Derivatives Exhibiting Antibacterial and Anti-Parasitic Activities

by Richard M. Beteck, Audrey Jordaan, Ronnett Seldon, Dustin Laming, Heinrich C. Hoppe, Digby F. Warner, Setshaba D. Khanye
Published 2021-02-01

New Quinolone-Based Thiosemicarbazones Showing Activity Against <i>Plasmodium falciparum</i> and <i>Mycobacterium tuberculosis</i>

by Richard M. Beteck, Ronnett Seldon, Audrey Jordaan, Digby F. Warner, Heinrich C. Hoppe, Dustin Laming, Setshaba D. Khanye
Published 2019-05-01

Isolation, Chemical Profile and Antimalarial Activities of Bioactive Compounds from Rauvolfia caffra Sond

by Dorcas B. Tlhapi, Isaiah D. I. Ramaite, Teunis Van Ree, Chinedu P. Anokwuru, Taglialatela-Scafati Orazio, Heinrich C. Hoppe
Published 2018-12-01

Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives

by Ayanda I. Zulu, Ogunyemi O. Oderinlo, Cuan Kruger, Michelle Isaacs, Heinrich C. Hoppe, Vincent J. Smith, Clinton G. L. Veale, Setshaba D. Khanye
Published 2020-04-01

Coumarin-Annulated Ferrocenyl 1,3-Oxazine Derivatives Possessing In Vitro Antimalarial and Antitrypanosomal Potency

by Mziyanda Mbaba, Laura M. K. Dingle, Ayanda I. Zulu, Dustin Laming, Tarryn Swart, Jo-Anne de la Mare, Heinrich C. Hoppe, Adrienne L. Edkins, Setshaba D. Khanye
Published 2021-03-01

Biological activities of plant extracts from Ficus elastica and Selaginella vogelli: An antimalarial, antitrypanosomal and cytotoxity evaluation

by Jean Emmanuel Mbosso Teinkela, Xavier Siwe Noundou, Edwige Laure Nguemfo, Franck Meyer, Rene Wintjens, Michelle Isaacs, Albert Emmanuel Mpondo Mpondo, Heinrich C. Hoppe, Rui Werner Maçedo Krause, Anatole Guy Blaise Azebaze
Published 2018-01-01

Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity

by Maureen Gumbo, Richard M. Beteck, Tawanda Mandizvo, Ronnett Seldon, Digby F. Warner, Heinrich C. Hoppe, Michelle Isaacs, Dustin Laming, Christina C. Tam, Luisa W. Cheng, Nicole Liu, Kirkwood M. Land, Setshaba D. Khanye
Published 2018-08-01