Puerarin inhibits hepatocellular carcinoma invasion and metastasis through miR-21-mediated PTEN/AKT signaling to suppress the epithelial-mesenchymal transition

by Yuan Zhou, Ruifeng Xue, Jinglin Wang, Haozhen Ren

Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization

by Jinglin Wang, Yang Liu, Haoran Ding, Xiaolei Shi, Haozhen Ren
Published 2021-01-01

Targeting PI3K/Akt/Nrf2 pathway by glabridin alleviates acetaminophen-induced hepatic injury in rats

by Hucheng Ma, Haozhen Ren, Jun Wang, Xianwen Yuan, Xinyu Wu, Xiaolei Shi
Published 2021-02-01

Down-Regulation of CXXC5 De-Represses MYCL1 to Promote Hepatic Stellate Cell Activation

by Xiaoyan Wu, Xiaoyan Wu, Xiaoyan Wu, Xiaoyan Wu, Wenhui Dong, Ming Kong, Haozhen Ren, Haozhen Ren, Jinglin Wang, Jinglin Wang, Longcheng Shang, Zhengyi Zhu, Wei Zhu, Xiaolei Shi, Xiaolei Shi
Published 2021-09-01

The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming

by Yang Liu, Haozhen Ren, Yuan Zhou, Longcheng Shang, Yuheng Zhang, Faji Yang, Xiaolei Shi
Published 2019-05-01

TNFα-Mediated Necroptosis Aggravates Ischemia-Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response

by Faji Yang, Longcheng Shang, Shuai Wang, Yang Liu, Haozhen Ren, Wei Zhu, Xiaolei Shi
Published 2019-01-01

Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts

by Yuan Zhou, Haozhen Ren, Bo Dai, Jun Li, Longcheng Shang, Jianfei Huang, Xiaolei Shi
Published 2018-12-01

Epiregulin (EREG) and Myocardin Related Transcription Factor A (MRTF-A) Form a Feedforward Loop to Drive Hepatic Stellate Cell Activation

by Xiaoyan Wu, Xiaoyan Wu, Xiaoyan Wu, Wenhui Dong, Tianyi Zhang, Haozhen Ren, Haozhen Ren, Jinglin Wang, Jinglin Wang, Longcheng Shang, Zhengyi Zhu, Wei Zhu, Xiaolei Shi, Xiaolei Shi, Yong Xu, Yong Xu
Published 2021-01-01

Ischemia reperfusion injury promotes recurrence of hepatocellular carcinoma in fatty liver via ALOX12-12HETE-GPR31 signaling axis

by Faji Yang, Yuheng Zhang, Haozhen Ren, Jinglin Wang, Longcheng Shang, Yang Liu, Wei Zhu, Xiaolei Shi
Published 2019-12-01

Serum response factor (SRF) promotes ROS generation and hepatic stellate cell activation by epigenetically stimulating NCF1/2 transcription

by Ming Kong, Xuyang Chen, Fangqiao Lv, Haozhen Ren, Zhiwen Fan, Hao Qin, Liming Yu, Xiaolei Shi, Yong Xu
Published 2019-09-01

SS-31 Protects Liver from Ischemia-Reperfusion Injury via Modulating Macrophage Polarization

by Longcheng Shang, Haozhen Ren, Shuai Wang, Hanyi Liu, Anyin Hu, Peng Gou, Yunzhen Lin, Jingchao Zhou, Wei Zhu, Xiaolei Shi
Published 2021-01-01

Inhibition of HMGB1 Suppresses Hepatocellular Carcinoma Progression via HIPK2-Mediated Autophagic Degradation of ZEB1

by Wei Zhu, Jun Li, Yuheng Zhang, Zhengyi Zhu, Hanyi Liu, Yunzhen Lin, Anyin Hu, Jingchao Zhou, Haozhen Ren, Xiaolei Shi
Published 2021-03-01