The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

by Joan Serrano, Jaroslava Seflova, Jihye Park, Marsha Pribadi, Keisuke Sanematsu, Noriatsu Shigemura, Vanida Serna, Fanchao Yi, Andrea Mari, Erik Procko, Richard E. Pratley, Seth L. Robia, George A. Kyriazis
Published 2021-12-01

T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

by Kathleen Smith, Elnaz Karimian Azari, Traci E. LaMoia, Tania Hussain, Veronika Vargova, Katalin Karolyi, Paula P. Veldhuis, Juan Pablo Arnoletti, Sebastian G. de la Fuente, Richard E. Pratley, Timothy F. Osborne, George A. Kyriazis
Published 2018-11-01

High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

by Joan Serrano, Kathleen R. Smith, Audra L. Crouch, Vandana Sharma, Fanchao Yi, Veronika Vargova, Traci E. LaMoia, Lydia M. Dupont, Vanida Serna, Fenfen Tang, Laisa Gomes-Dias, Joshua J. Blakeslee, Emmanuel Hatzakis, Scott N. Peterson, Matthew Anderson, Richard E. Pratley, George A. Kyriazis
Published 2021-01-01