Functional Dynamics of Proteins

by Lee-Wei Yang, Silvina Matysiak, Shang-Te Danny Hsu, Gabriela Mustata Wilson, Yasumasa Joti
Published 2012-01-01

Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.

by Elizabeth R Sharlow, Gabriela Mustata Wilson, David Close, Stephanie Leimgruber, Manuj Tandon, Robyn B Reed, Tong Ying Shun, Q Jane Wang, Peter Wipf, John S Lazo
Published 2011-01-01

Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen.

by Elizabeth R Sharlow, David Close, Tongying Shun, Stephanie Leimgruber, Robyn Reed, Gabriela Mustata, Peter Wipf, Jacob Johnson, Michael O'Neil, Max Grögl, Alan J Magill, John S Lazo
Published 2009-11-01

A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity.

by Elizabeth R Sharlow, Todd A Lyda, Heidi C Dodson, Gabriela Mustata, Meredith T Morris, Stephanie S Leimgruber, Kuo-Hsiung Lee, Yoshiki Kashiwada, David Close, John S Lazo, James C Morris
Published 2010-04-01

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

by Jing Zhao, Lei Zhang, Xiaodong Mu, Christelle Doebelin, William Nguyen, Callen Wallace, Daniel P Reay, Sara J McGowan, Lana Corbo, Paula R Clemens, Gabriela Mustata Wilson, Simon C Watkins, Laura A Solt, Michael D Cameron, Johnny Huard, Laura J Niedernhofer, Theodore M Kamenecka, Paul D Robbins
Published 2018-06-01