Hydroxysteroid dehydrogenase HSD1L is localised to the pituitary–gonadal axis of primates

by A Daniel Bird, Spencer Greatorex, David Reser, Gareth G Lavery, Timothy J Cole
Published 2017-09-01

Sorafenib-Induced Apoptosis in Hepatocellular Carcinoma Is Reversed by SIRT1

by Antje Garten, Theresa Grohmann, Katarina Kluckova, Gareth G. Lavery, Wieland Kiess, Melanie Penke
Published 2019-08-01

Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid[S]

by Carlos A. Penno, Stuart A. Morgan, Anna Vuorinen, Daniela Schuster, Gareth G. Lavery, Alex Odermatt
Published 2013-10-01

The Role of Metabolism in Migraine Pathophysiology and Susceptibility

by Olivia Grech, Susan P. Mollan, Benjamin R. Wakerley, Daniel Fulton, Gareth G. Lavery, Alexandra J. Sinclair
Published 2021-05-01

Calcitonin gene related peptide monoclonal antibody treats headache in patients with active idiopathic intracranial hypertension

by Andreas Yiangou, James L. Mitchell, Vivek Vijay, Olivia Grech, Edward Bilton, Gareth G. Lavery, Claire Fisher, Julie Edwards, Susan P. Mollan, Alexandra J. Sinclair
Published 2020-09-01

Intracranial pressure directly predicts headache morbidity in idiopathic intracranial hypertension

by S. P. Mollan, B. R. Wakerley, Z. Alimajstorovic, J. Mitchell, R. Ottridge, A. Yiangou, M. Thaller, A. Gupta, O. Grech, G. Lavery, K. Brock, A. J. Sinclair
Published 2021-10-01

11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy

by C. G. Fenton, C. L. Doig, S. Fareed, A. Naylor, A. P. Morrell, O. Addison, C. Wehmeyer, C. D. Buckley, M. S. Cooper, G. G. Lavery, K. Raza, R. S. Hardy
Published 2019-08-01

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis

by Justine M. Webster, Michael S. Sagmeister, Chloe G. Fenton, Alex P. Seabright, Yu-Chiang Lai, Simon W. Jones, Andrew Filer, Mark S. Cooper, Gareth G. Lavery, Karim Raza, Ramon Langen, Rowan S. Hardy
Published 2021-07-01

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion [version 2; peer review: 2 approved]

by Lucy A. Oakey, Rachel S. Fletcher, Yasir S. Elhassan, David M. Cartwright, Craig L. Doig, Antje Garten, Alpesh Thakker, Oliver D. K. Maddocks, Tong Zhang, Daniel A. Tennant, Christian Ludwig, Gareth G. Lavery
Published 2019-09-01

Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin

by Beom Jun Kim, Noo Ri Lee, Chung Hyeok Lee, Young Bin Lee, Sung Jay Choe, Solam Lee, Hyun Jee Hwang, Eunjung Kim, Gareth G. Lavery, Kyong-Oh Shin, Kyungho Park, Eung Ho Choi
Published 2021-05-01

Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction

by Craig L. Doig, Agnieszka E. Zielinska, Rachel S. Fletcher, Lucy A. Oakey, Yasir S. Elhassan, Antje Garten, David Cartwright, Silke Heising, Ahmed Alsheri, David G. Watson, Cornelia Prehn, Jerzy Adamski, Daniel A. Tennant, Gareth G. Lavery
Published 2020-02-01

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

by Rachel S. Fletcher, Joanna Ratajczak, Craig L. Doig, Lucy A. Oakey, Rebecca Callingham, Gabriella Da Silva Xavier, Antje Garten, Yasir S. Elhassan, Philip Redpath, Marie E. Migaud, Andrew Philp, Charles Brenner, Carles Canto, Gareth G. Lavery
Published 2017-08-01

Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

by C. G. Fenton, J. M. Webster, C. S. Martin, S. Fareed, C. Wehmeyer, H. Mackie, R. Jones, A. P. Seabright, J. W. Lewis, Y. C. Lai, C. S. Goodyear, S. W Jones, M. S. Cooper, G. G. Lavery, R. Langen, K. Raza, R. S. Hardy
Published 2019-08-01

A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis

by Matthew C. Sinton, Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin, Sara Wernig-Zorc, John P. Thomson, Roderick N. Carter, Marcus J. Lyall, Paul D. Walker, Alpesh Thakker, Richard R. Meehan, Gareth G. Lavery, Nicholas M. Morton, Christian Ludwig, Daniel A. Tennant, David C. Hay, Amanda J. Drake
Published 2021-01-01

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

by Yasir S. Elhassan, Katarina Kluckova, Rachel S. Fletcher, Mark S. Schmidt, Antje Garten, Craig L. Doig, David M. Cartwright, Lucy Oakey, Claire V. Burley, Ned Jenkinson, Martin Wilson, Samuel J.E. Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel A. Tennant, Peter Nightingale, Gareth A. Wallis, Konstantinos N. Manolopoulos, Charles Brenner, Andrew Philp, Gareth G. Lavery
Published 2019-08-01

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion

by Katrina Viloria, Daniela Nasteska, Linford J.B. Briant, Silke Heising, Dean P. Larner, Nicholas H.F. Fine, Fiona B. Ashford, Gabriela da Silva Xavier, Maria Jiménez Ramos, Annie Hasib, Federica Cuozzo, Jocelyn E. Manning Fox, Patrick E. MacDonald, Ildem Akerman, Gareth G. Lavery, Christine Flaxman, Noel G. Morgan, Sarah J. Richardson, Martin Hewison, David J. Hodson
Published 2020-06-01