Identification of Novel Src Inhibitors: Pharmacophore-Based Virtual Screening, Molecular Docking and Molecular Dynamics Simulations

by Yi Zhang, Ting-jian Zhang, Shun Tu, Zhen-hao Zhang, Fan-hao Meng
Published 2020-09-01

Synthesis and biological evaluation of novel (E)-N'-benzylidene hydrazides as novel c-Met inhibitors through fragment based virtual screening

by Jing-wei Liang, Shi-long Li, Shan Wang, Wan-qiu Li, Fan-hao Meng
Published 2020-01-01

An Integrated Network, RNA Sequencing, and Experiment Pharmacology Approach Reveals the Active Component, Potential Target, and Mechanism of Gelsemium elegans in the Treatment of C...

by Lin Wang, Hai-li Xu, Jing-wei Liang, Ying-ying Ding, Fan-hao Meng
Published 2020-12-01

Ultra-Liquid Chromatography Tandem Mass Spectrometry (UPLC-MS/MS)-Based Pharmacokinetics and Tissue Distribution Study of Koumine and the Detoxification Mechanism of Glycyrrhiza ur...

by Lin Wang, Qi Sun, Nan Zhao, Yan-Qing Wen, Yang Song, Fan-Hao Meng
Published 2018-07-01

Fragment-Based Structural Optimization of a Natural Product Itampolin A as a p38α Inhibitor for Lung Cancer

by Jing-wei Liang, Ming-yang Wang, Shan Wang, Xin-yang Li, Fan-hao Meng
Published 2019-01-01

Synthesis and Biological Evaluation of New Substituted 3-[4-(Phenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one Derivatives as α-Glucosidase Inhibitors

by Yu-ling Wang, Ting-jian Zhang, Jing-wei Liang, Fan-hao Meng, Shao-jie Wang
Published 2014-01-01

A Comprehensive In Silico Method to Study the QSTR of the Aconitine Alkaloids for Designing Novel Drugs

by Ming-Yang Wang, Jing-Wei Liang, Kamara Mohamed Olounfeh, Qi Sun, Nan Zhao, Fan-Hao Meng
Published 2018-09-01

Identification of novel CDK2 inhibitors by a multistage virtual screening method based on SVM, pharmacophore and docking model

by Jing-Wei Liang, Ming-Yang Wang, Shan Wang, Shi-Long Li, Wan-Qiu Li, Fan-Hao Meng
Published 2020-01-01

A metabonomic analysis of serum from rats treated with ricinine using ultra performance liquid chromatography coupled with mass spectrometry.

by Jing Peng, Shuang Cai, Lin Wang, Nan Zhao, Ting-jian Zhang, Zai-xing Chen, Fan-hao Meng
Published 2014-01-01

Inflammation-mediated age-dependent effects of casein kinase 2-interacting protein-1 on osteogenesis in mesenchymal stem cells

by Xiao-Guang Tian, Fei-Fei Gong, Xi Li, Fan-Hao Meng, Zheng Zhou, Hai-Zhong Zhang, Ning-Ning Wang
Published 2020-08-01

Development and Validation of a Sensitive UHPLC-MS/MS Method for the Measurement of Gardneramine in Rat Plasma and Tissues and Its Application to Pharmacokinetics and Tissue Distri...

by Nan Zhao, Hao-ran Tan, Qi-li Chen, Qi Sun, Lin Wang, Yang Song, Kamara Mohamed Olounfeh, Fan-hao Meng
Published 2019-10-01

Study of Imidazolium Salt Derivatives as PIK3CA Inhibitors Using a Comprehensive in Silico Method

by Ming-yang Wang, Jing-wei Liang, Xin-yang Li, Kamara Mohamed Olounfeh, Shi-long Li, Shan Wang, Lin Wang, Fan-hao Meng
Published 2018-03-01

Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibiting angiogenesis in NSCLC

by Xin-yang Li, De-pu Wang, Guo-qing Lu, Kai-li Liu, Ting-jian Zhang, Shuai Li, Kamara Mohamed O, Wen-han Xue, Xin-hua Qian, Fan-hao Meng
Published 2020-11-01