Inhibitors of sterol synthesis. Chemical synthesis of 5 beta-cholest-8-ene-3 beta,15 alpha-diol and its effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K...

by W K Wilson, F D Pinkerton, N D Kirkpatrick, G J Schroepfer, Jr
Published 1989-06-01

Inhibitors of sterol synthesis. Effects of a new fluorinated analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one in rats.

by N Gerst, F D Pinkerton, A Kisic, W K Wilson, S Swaminathan, G.J. Schroepfer, Jr.
Published 1994-06-01

Inhibitors of sterol synthesis. Metabolism-based design and construction of a new analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects in cultured mammalian cel...

by S Swaminathan, A U Siddiqui, N Gerst, F D Pinkerton, A Kisic, L J Kim, W K Wilson, G J Schroepfer
Published 1995-04-01

Inhibitors of sterol synthesis. Submicromolar 14 alpha-ethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol causes a major modification of the sterol composition of CHO-K1 cells and a...

by A Izumi, F.D Pinkerton, S.O Nelson, J.S Pyrek, P.J Neill, J H Smith, G.J Schroepfer, Jr
Published 1994-07-01

Inhibitors of sterol synthesis. Chemical synthesis, structure, and biological activities of (25R)-3 beta,26-dihydroxy-5 alpha-cholest-8(14)-en-15-one, a metabolite of 3 beta-hydrox...

by H S Kim, W K Wilson, D H Needleman, F D Pinkerton, D K Wilson, F A Quiocho, G J Schroepfer, Jr
Published 1989-02-01