High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions

by Lai, Yong, Cui, Liang, Babunovic, Gregory H, Fortune, Sarah M, Doench, John G, Lu, Timothy K
Published 2022

Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens

by Lai, Yong, Babunovic, Gregory H, Cui, Liang, Dedon, Peter C, Doench, John G, Fortune, Sarah M, Lu, Timothy K
Published 2021

Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression

by Janas, Maja M., Love, Tara, Harris, Abigail S., Stevenson, Kristen, Semmelmann, Karlheinz, Shaffer, Jonathan M., Chen, Po-Hao, Doench, John G., Yerramilli, Subrahmanyam V.B.K, Neuberg, Donna S., Iliopoulos, Dimitrios, Novina, Carl D., Wang, Eric T, Housman, David E, Burge, Christopher B
Published 2014

PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

by Collins, Natalie B, Al Abosy, Rose, Miller, Brian C, Bi, Kevin, Zhao, Qihong, Quigley, Michael, Ishizuka, Jeffrey J, Yates, Kathleen B, Pope, Hans W, Manguso, Robert T, Shrestha, Yashaswi, Wadsworth, Marc, Hughes, Travis, Shalek, Alex K, Boehm, Jesse S, Hahn, William C, Doench, John G, Haining, W Nicholas
Published 2022

Synergistic interactions with PI3K inhibition that induce apoptosis

by Zwang, Yaara, Chen, Casandra, Rinne, Mikael L, Doench, John G, Piccioni, Federica, Tan, Li, Huang, Hai-Tsang, Wang, Jinhua, Ham, Young Jin, O'Connell, Joyce, Bhola, Patrick, Doshi, Mihir, Whitman, Matthew, Letai, Anthony, Root, David E, Gray, Nathanael, Hahn, William C, Jonas, Oliver H., Langer, Robert S, Cima, Michael J.
Published 2017

Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma

by Chapuy, Bjoern, McKeown, Michael R, Lin, Charles Y, Monti, Stefano, Roemer, Margaretha G.M, Qi, Jun, Rahl, Peter B, Sun, Heather H, Yeda, Kelly T, Doench, John G, Reichert, Elaine, Kung, Andrew L, Rodig, Scott J, Young, Richard A, Shipp, Margaret A, Bradner, James E, Young, Richard A.
Published 2016