Protein clearance mechanisms and their demise in age-related neurodegenerative diseases

by Isabel Saez, David Vilchez
Published 2015-01-01

Induced pluripotent stem cells from Huntington’s disease patients: a promising approach to define and correct disease-related alterations

by Azra Fatima, Ricardo Gutiérrez-Garcia, David Vilchez
Published 2019-01-01

Proteostasis of Huntingtin in Health and Disease

by Seda Koyuncu, Azra Fatima, Ricardo Gutierrez-Garcia, David Vilchez
Published 2017-07-01

Searching for Selective Scaffolds against <em>Plasmodium falciparum</em> Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase

by Antonio Viayna, David Vílchez, Javier Vázquez, Susana Pérez-Benavente, José Manuel Bautista, Francisco Javier Luque
Published 2019-08-01

Author Correction: The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients

by Seda Koyuncu, Isabel Saez, Hyun Ju Lee, Ricardo Gutierrez-Garcia, Wojciech Pokrzywa, Azra Fatima, Thorsten Hoppe, David Vilchez
Published 2020-02-01

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients

by Seda Koyuncu, Isabel Saez, Hyun Ju Lee, Ricardo Gutierrez-Garcia, Wojciech Pokrzywa, Azra Fatima, Thorsten Hoppe, David Vilchez
Published 2018-07-01

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan

by Alireza Noormohammadi, Amirabbas Khodakarami, Ricardo Gutierrez-Garcia, Hyun Ju Lee, Seda Koyuncu, Tim König, Christina Schindler, Isabel Saez, Azra Fatima, Christoph Dieterich, David Vilchez
Published 2016-11-01

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells

by Hyun Ju Lee, Deniz Bartsch, Cally Xiao, Santiago Guerrero, Gaurav Ahuja, Christina Schindler, James J. Moresco, John R. Yates, Fátima Gebauer, Hisham Bazzi, Christoph Dieterich, Leo Kurian, David Vilchez
Published 2017-11-01

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy

by Caroline Kumsta, Jessica T. Chang, Reina Lee, Ee Phie Tan, Yongzhi Yang, Rute Loureiro, Elizabeth H. Choy, Shaun H. Y. Lim, Isabel Saez, Alexander Springhorn, Thorsten Hoppe, David Vilchez, Malene Hansen
Published 2019-12-01