Intoxication of host cells by the T3SS phospholipase ExoU: PI(4,5)P2-associated, cytoskeletal collapse and late phase membrane blebbing.

by Hiromi Sato, Dara W Frank
Published 2014-01-01

Five mechanisms of manipulation by bacterial effectors: a ubiquitous theme.

by David M Anderson, Dara W Frank
Published 2012-01-01

Cross Kingdom Activators of Five Classes of Bacterial Effectors.

by David M Anderson, Jimmy B Feix, Dara W Frank
Published 2015-07-01

Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosa.

by Hiromi Sato, Meredith L Hunt, Joshua J Weiner, Andrew T Hansen, Dara W Frank
Published 2011-03-01

Structure and Dynamics of Type III Secretion Effector Protein ExoU As determined by SDSL-EPR Spectroscopy in Conjunction with De Novo Protein Folding

by Axel W. Fischer, David M. Anderson, Maxx H. Tessmer, Dara W. Frank, Jimmy B. Feix, Jens Meiler
Published 2017-06-01

Pseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells.

by Ron Balczon, Nutan Prasain, Cristhiaan Ochoa, Jason Prater, Bing Zhu, Mikhail Alexeyev, Sarah Sayner, Dara W Frank, Troy Stevens
Published 2013-01-01

A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge.

by Roger D Pechous, Travis R McCarthy, Nrusingh P Mohapatra, Shilpa Soni, Renee M Penoske, Nita H Salzman, Dara W Frank, John S Gunn, Thomas C Zahrt
Published 2008-06-01

In the absence of effector proteins, the Pseudomonas aeruginosa type three secretion system needle tip complex contributes to lung injury and systemic inflammatory responses.

by Jonathon P Audia, Ashley S Lindsey, Nicole A Housley, Courtney R Ochoa, Chun Zhou, Michie Toba, Masahiko Oka, Naga S Annamdevula, Meshann S Fitzgerald, Dara W Frank, Diego F Alvarez
Published 2013-01-01

Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.

by Michael A Apicella, Deborah M B Post, Andrew C Fowler, Bradley D Jones, Jed A Rasmussen, Jason R Hunt, Sayaka Imagawa, Biswa Choudhury, Thomas J Inzana, Tamara M Maier, Dara W Frank, Thomas C Zahrt, Kathryn Chaloner, Michael P Jennings, Molly K McLendon, Bradford W Gibson
Published 2010-07-01