Broader Implications of Defining Standards for the Pluripotency of iPSCs

by Daley, George Q., Lensch, M. William, Jaenisch, Rudolf, Meissner, Alexander, Plath, Kathrin, Yamanaka, Shinya
Published 2015

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling

by Chandrasekaran, Sriram, Zhang, Jin, Sun, Zhen, Zhang, Li, Ross, Christian A., Huang, Yu-Chung, Asara, John M., Li, Hu, Daley, George Q., Collins, James J.
Published 2018

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

by Unternaehrer, Juli J, Zhao, Rui, Kim, Kitai, Cesana, Marcella, Powers, John T, Ratanasirintrawoot, Sutheera, Onder, Tamer T., Shibue, Tsukasa, Weinberg, Robert A, Daley, George Q., Weinberg, Robert A
Published 2015

Reconstruction of complex single-cell trajectories using CellRouter

by Lummertz da Rocha, Edroaldo, Rowe, R. Grant, Lundin, Vanessa, Malleshaiah, Mohan, Jha, Deepak Kumar, Rambo, Carlos R., Li, Hu, North, Trista E., Collins, James J., Daley, George Q.
Published 2018

A systems biology pipeline identifies regulatory networks for stem cell engineering

by Kinney, Melissa A., Vo, Linda T., Frame, Jenna M., Barragan, Jessica, Conway, Ashlee J., Li, Shuai, Wong, Kwok-Kin, Collins, James J., Cahan, Patrick, North, Trista E., Lauffenburger, Douglas A, Daley, George Q.
Published 2020

Chromatin-modifying enzymes as modulators of reprogramming

by Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Marcarci, B. Ogan, Unternaehrer, Juli, Armstrong, Scott A., Daley, George Q., Gupta, Piyush, Lander, Eric Steven
Published 2014

Deconstructing transcriptional heterogeneity in pluripotent stem cells

by Kumar, Roshan M., Cahan, Patrick, Shalek, Alex K., Satija, Rahul, DaleyKeyser, AJay, Li, Hu, Zhang, Jin, Pardee, Keith, Gennert, David, Trombetta, John J., Ferrante, Thomas C., Regev, Aviv, Daley, George Q., Collins, James J.
Published 2015

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

by Guttman, Mitchell, Loewer, Sabine, Cabili, Moran N., Loh, Yuin-Han, Thomas, Kelly, Park, In Hyun, Garber, Manuel, Curran, Matthew, Onder, Tamer T., Agarwal, Suneet, Manos, Philip D., Datta, Sumon, Schlaeger, Thorsten M., Daley, George Q., Rinn, John L., Lander, Eric Steven
Published 2012

The Lin28/let-7 Axis Regulates Glucose Metabolism

by Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V, Shinoda, Gen, Shah, Samar P, Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse Michael, Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.
Published 2014

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

by Xu, Cong, Fan, Zi Peng, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G, Daley, George Q., Schier, Alexander F, Young, Richard A, Zon, Leonard I, Muller, Patrick, Young, Richard A.
Published 2014

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

by Kharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William S., Lane, Steven W., Scholl, Claudia, Frohling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf, Daley, George Q.
Published 2012

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

by Cacchiarelli, Davide, Trapnell, Cole, Ziller, Michael J, Soumillon, Magali, Cesana, Marcella, Karnik, Rahul, Donaghey, Julie, Smith, Zachary D, Ratanasirintrawoot, Sutheera, Zhang, Xiaolan, Ho Sui, Shannan J, Wu, Zhaoting, Akopian, Veronika, Gifford, Casey A, Doench, John, Rinn, John L, Daley, George Q, Meissner, Alexander, Mikkelsen, Tarjei S, Lander, Eric Steven
Published 2017

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma

by Powers, John T., Tsanov, Kaloyan M., Pearson, Daniel S., Roels, Frederik, Spina, Catherine S., Ebright, Richard, Seligson, Marc, de Soysa, Yvanka, Cahan, Patrick, Theißen, Jessica, Tu, Ho-Chou, Han, Areum, Kurek, Kyle C., LaPier, Grace S., Osborne, Jihan K., Ross, Samantha J., Cesana, Marcella, Collins, James J., Berthold, Frank, Daley, George Q.
Published 2017

Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

by Trompouki, Eirini, Bowman, Teresa V, Lawton, Lee N., Fan, Zi Peng, Wu, Dai-Chen, DiBiase, Anthony, Martin, Corey S, Cech, Jennifer N., Sessa, Anna K, Leblanc, Jocelyn L, Li, Pulin, Durand, Ellen M, Mosimann, Christian, Heffner, Garrett C, Daley, George Q., Paulson, Robert F, Young, Richard A, Zon, Leonard I
Published 2014

Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival

by Yi, Caroline H, Pan, Heling, Seebacher, Jan, Jang, Il-Ho, Hyberts, Sven G, Heffron, Gregory J., Vander Heiden, Matthew G, Yang, Renliang, Li, Fupeng, Locasale, Jason W., Sharfi, Hadar, Zhai, Bo, Rodriguez-Mias, Ricard, Luithardt, Harry, Cantley, Lewis C., Daley, George Q., Asara, John M., Gygi, Steven P., Wagner, Gerhard, Liu, Chuan-Fa, Yuan, Junying
Published 2014

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

by Yang, Bin Xia, EL Farran, Chadi A, Guo, Hong Chao, Yu, Tao, Fang, Hai Tong, Wang, Hao Fei, Schlesinger, Sharon, Seah, Yu Fen Samantha, Goh, Germaine Yen Lin, Neo, Suat Peng, Li, Yinghui, Lorincz, Matthew C, Tergaonkar, Vinay, Lim, Tit-Meng, Chen, Lingyi, Gunaratne, Jayantha, Goff, Stephen P, Daley, George Q, Li, Hu, Bard, Frederic A, Loh, Yuin-Han, Collins, James J.
Published 2017

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

by Doulatov, Sergei, Vo, Linda T., Macari, Elizabeth R., Wahlster, Lara, Kinney, Melissa A., Taylor, Alison M., Barragan, Jessica, Gupta, Manav, McGrath, Katherine, Humphries, Jessica M., DeVine, Alex, Narla, Anupama, Alter, Blanche P., Beggs, Alan H., Agarwal, Suneet, Ebert, Benjamin L., Gazda, Hanna T., Sieff, Colin A., Schlaeger, Thorsten M., Zon, Leonard I., Daley, George Q., Lee, Hsiang-Ying, Lodish, Harvey F
Published 2018