Lipidomics and the quest for brainy lipids

by Cristina Legido-Quigley
Published 2021-03-01

Palmitate and Stearate are Increased in the Plasma in a 6-OHDA Model of Parkinson’s Disease

by Anuri Shah, Pei Han, Mung-Yee Wong, Raymond Chuen-Chung Chang, Cristina Legido-Quigley
Published 2019-02-01

Metabolomic method: UPLC-q-ToF polar and non-polar metabolites in the healthy rat cerebellum using an in-vial dual extraction.

by Amera A Ebshiana, Stuart G Snowden, Madhav Thambisetty, Richard Parsons, Abdul Hye, Cristina Legido-Quigley
Published 2015-01-01

Metabolomic Assessment Reveals Alteration in Polyols and Branched Chain Amino Acids Associated With Present and Future Renal Impairment in a Discovery Cohort of 637 Persons With Ty...

by Nete Tofte, Tommi Suvitaival, Kajetan Trost, Ismo Matias Mattila, Simone Theilade, Signe Abitz Winther, Signe Abitz Winther, Tarunveer Singh Ahluwalia, Marie Frimodt-Møller, Cristina Legido-Quigley, Cristina Legido-Quigley, Peter Rossing, Peter Rossing
Published 2019-11-01

Metabolic phenotyping in the mouse model of urinary tract infection shows that 3-hydroxybutyrate in plasma is associated with infection.

by Pei Han, Yong Huang, Yumin Xie, Wu Yang, Yaoyao Wang, Wenying Xiang, Peter J Hylands, Cristina Legido-Quigley
Published 2017-01-01

Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis

by Khadija M. Alawi, David Tandio, Jin Xu, Pratish Thakore, Georgia Papacleovoulou, Elizabeth S. Fernandes, Cristina Legido-Quigley, Catherine Williamson, Susan D. Brain
Published 2017-05-01

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study.

by Stuart G Snowden, Amera A Ebshiana, Abdul Hye, Yang An, Olga Pletnikova, Richard O'Brien, John Troncoso, Cristina Legido-Quigley, Madhav Thambisetty
Published 2017-03-01

Lipidomics of human adipose tissue reveals diversity between body areas.

by Naba Al-Sari, Tommi Suvitaival, Ismo Mattila, Ashfaq Ali, Linda Ahonen, Kajetan Trost, Trine Foged Henriksen, Flemming Pociot, Lars Ove Dragsted, Cristina Legido-Quigley
Published 2020-01-01

The Impact of Ischemia/Reperfusion Injury on Liver Allografts from Deceased after Cardiac Death versus Deceased after Brain Death Donors.

by Jin Xu, Blayne Amir Sayed, Ana Maria Casas-Ferreira, Parthi Srinivasan, Nigel Heaton, Mohammed Rela, Yun Ma, Susan Fuggle, Cristina Legido-Quigley, Wayel Jassem
Published 2016-01-01

Deregulation of the Purine Pathway in Pre-Transplant Liver Biopsies Is Associated with Graft Function and Survival after Transplantation

by Jin Xu, Mohammad Hassan-Ally, Ana María Casas-Ferreira, Tommi Suvitaival, Yun Ma, Hector Vilca-Melendez, Mohamed Rela, Nigel Heaton, Jassem Wayel, Cristina Legido-Quigley
Published 2020-03-01

Blood Metabolite Signatures of Metabolic Syndrome in Two Cross-Cultural Older Adult Cohorts

by Uma V. Mahajan, Vijay R. Varma, Chiung-Wei Huang, Yang An, Toshiko Tanaka, Luigi Ferrucci, Toru Takebayashi, Sei Harada, Miho Iida, Cristina Legido-Quigley, Madhav Thambisetty
Published 2020-02-01

Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication⋆

by Mads Israelsen, Min Kim, Tommi Suvitaival, Bjørn Stæhr Madsen, Camilla Dalby Hansen, Nikolaj Torp, Kajetan Trost, Maja Thiele, Torben Hansen, Cristina Legido-Quigley, Aleksander Krag
Published 2021-10-01

Author Correction: Intravital imaging of islet Ca2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

by Elina Akalestou, Kinga Suba, Livia Lopez-Noriega, Eleni Georgiadou, Pauline Chabosseau, Alasdair Gallie, Asger Wretlind, Cristina Legido-Quigley, Isabelle Leclerc, Victoria Salem, Guy A. Rutter
Published 2021-09-01

Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post‐hoc analysis of a randomized crossover trial

by Naba Al‐Sari, Signe Schmidt, Tommi Suvitaival, Min Kim, Kajetan Trošt, Ajenthen G. Ranjan, Merete B. Christensen, Anne J. Overgaard, Flemming Pociot, Kirsten Nørgaard, Cristina Legido‐Quigley
Published 2021-04-01

Plasma Proteomic Biomarkers Relating to Alzheimer’s Disease: A Meta-Analysis Based on Our Own Studies

by Liu Shi, Noel J. Buckley, Isabelle Bos, Isabelle Bos, Sebastiaan Engelborghs, Sebastiaan Engelborghs, Kristel Sleegers, Kristel Sleegers, Giovanni B. Frisoni, Anders Wallin, Alberto Lléo, Julius Popp, Julius Popp, Pablo Martinez-Lage, Cristina Legido-Quigley, Cristina Legido-Quigley, Frederik Barkhof, Frederik Barkhof, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Pieter Jelle Visser, Pieter Jelle Visser, Lars Bertram, Lars Bertram, Simon Lovestone, Simon Lovestone, Alejo J. Nevado-Holgado
Published 2021-07-01

Correction: Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic st...

by Uma V Mahajan, Vijay R Varma, Michael E Griswold, Chad T Blackshear, Yang An, Anup M Oommen, Sudhir Varma, Juan C Troncoso, Olga Pletnikova, Richard O'Brien, Timothy J Hohman, Cristina Legido-Quigley, Madhav Thambisetty
Published 2020-10-01

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study.

by Uma V Mahajan, Vijay R Varma, Michael E Griswold, Chad T Blackshear, Yang An, Anup M Oommen, Sudhir Varma, Juan C Troncoso, Olga Pletnikova, Richard O'Brien, Timothy J Hohman, Cristina Legido-Quigley, Madhav Thambisetty
Published 2020-01-01

Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s disease

by Jin Xu, Giulia Bankov, Min Kim, Asger Wretlind, Jodie Lord, Rebecca Green, Angela Hodges, Abdul Hye, Dag Aarsland, Latha Velayudhan, Richard J. B. Dobson, Petroula Proitsi, Cristina Legido-Quigley, on behalf of the AddNeuroMed Consortium
Published 2020-09-01

Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a targeted metabolomic and transcriptomic study

by Vijay R. Varma, H. Büşra Lüleci, Anup M. Oommen, Sudhir Varma, Chad T. Blackshear, Michael E. Griswold, Yang An, Jackson A. Roberts, Richard O’Brien, Olga Pletnikova, Juan C. Troncoso, David A. Bennett, Tunahan Çakır, Cristina Legido-Quigley, Madhav Thambisetty
Published 2021-06-01

Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s...

by Luke Whiley, Katie E. Chappell, Ellie D’Hondt, Matthew R. Lewis, Beatriz Jiménez, Stuart G. Snowden, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Jonathan R. Swann, Abdul Hye, Simon Lovestone, Cristina Legido-Quigley, Elaine Holmes, on behalf of AddNeuroMed consortium
Published 2021-01-01