Human Leukocytes Kill Brugia malayi Microfilariae Independently of DNA-Based Extracellular Trap Release.

by Ciaran J McCoy, Barbara J Reaves, Steeve Giguère, Ruby Coates, Balázs Rada, Adrian J Wolstenholme
Published 2017-01-01

Recognition and killing of Brugia malayi microfilariae by human immune cells is dependent on the parasite sample and is not altered by ivermectin treatment

by Barbara J. Reaves, Connor Wallis, Ciaran J. McCoy, W. Walter Lorenz, Balazs Rada, Adrian J. Wolstenholme
Published 2018-12-01

New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

by Ciaran J. McCoy, Louise E. Atkinson, Mostafa Zamanian, Paul McVeigh, Tim A. Day, Michael J. Kimber, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Published 2014-06-01

flp-32 Ligand/receptor silencing phenocopy faster plant pathogenic nematodes.

by Louise E Atkinson, Michael Stevenson, Ciaran J McCoy, Nikki J Marks, Colin Fleming, Mostafa Zamanian, Tim A Day, Michael J Kimber, Aaron G Maule, Angela Mousley
Published 2013-02-01

Evaluation of changes in drug susceptibility and population genetic structure in Haemonchus contortus following worm replacement as a means to reverse the impact of multiple-anthel...

by Melissa M. George, Adriano F. Vatta, Sue B. Howell, Bob E. Storey, Ciaran J. McCoy, Adrian J. Wolstenholme, Elizabeth M. Redman, John S. Gilleard, Ray M. Kaplan
Published 2021-04-01

EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor.

by Shivani Choudhary, Samuel K Buxton, Sreekanth Puttachary, Saurabh Verma, Gunnar R Mair, Ciaran J McCoy, Barbara J Reaves, Adrian J Wolstenholme, Richard J Martin, Alan P Robertson
Published 2020-04-01

Phylum-Spanning Neuropeptide GPCR Identification and Prioritization: Shaping Drug Target Discovery Pipelines for Nematode Parasite Control

by Louise E. Atkinson, Ciaran J. McCoy, Bethany A. Crooks, Fiona M. McKay, Paul McVeigh, Darrin McKenzie, Allister Irvine, John Harrington, Bruce A. Rosa, Bruce A. Rosa, Makedonka Mitreva, Makedonka Mitreva, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Published 2021-09-01