MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation

by Cristina Batlle, Isabel Calvo, Valentin Iglesias, Cian J. Lynch, Marcos Gil-Garcia, Manuel Serrano, Salvador Ventura
Published 2021-03-01

Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19

by Raquel Bernad, Cian J. Lynch, Rocio G. Urdinguio, Camille Stephan-Otto Attolini, Mario F. Fraga, Manuel Serrano
Published 2021-04-01

Dissection of two routes to naïve pluripotency using different kinase inhibitors

by Ana Martinez-Val, Cian J. Lynch, Isabel Calvo, Pilar Ximénez-Embún, Fernando Garcia, Eduardo Zarzuela, Manuel Serrano, Javier Munoz
Published 2021-03-01

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.

by Cian J Lynch, Zahid H Shah, Simon J Allison, Shafiq U Ahmed, Jack Ford, Lorna J Warnock, Han Li, Manuel Serrano, Jo Milner
Published 2010-10-01

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

by Cian J. Lynch, Raquel Bernad, Isabel Calvo, Sandrina Nóbrega-Pereira, Sergio Ruiz, Nuria Ibarz, Ana Martinez-Val, Osvaldo Graña-Castro, Gonzalo Gómez-López, Eduardo Andrés-León, Vladimir Espinosa Angarica, Antonio del Sol, Sagrario Ortega, Oscar Fernandez-Capetillo, Enrique Rojo, Javier Munoz, Manuel Serrano
Published 2018-01-01