Brain–gut–adipose-tissue communication pathways at a glance

by Chun-Xia Yi, Matthias H. Tschöp
Published 2012-09-01

High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

by Chun-Xia Yi, Matthias H. Tschöp, Stephen C. Woods, Susanna M. Hofmann
Published 2012-09-01

Mapping of Microglial Brain Region, Sex and Age Heterogeneity in Obesity

by Irina V. Milanova, Felipe Correa-da-Silva, Andries Kalsbeek, Chun-Xia Yi
Published 2021-03-01

The Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia

by Samantha E. C. Wolff, Samantha E. C. Wolff, Samantha E. C. Wolff, Xiao-Lan Wang, Xiao-Lan Wang, Xiao-Lan Wang, Han Jiao, Jia Sun, Andries Kalsbeek, Andries Kalsbeek, Andries Kalsbeek, Chun-Xia Yi, Chun-Xia Yi, Chun-Xia Yi, Yuanqing Gao
Published 2020-09-01

Time-Restricted Feeding Improves Glucose Tolerance in Rats, but Only When in Line With the Circadian Timing System

by Paul de Goede, Paul de Goede, Ewout Foppen, Ewout Foppen, Wayne I. G. R. Ritsema, Wayne I. G. R. Ritsema, Nikita L. Korpel, Nikita L. Korpel, Chun-Xia Yi, Chun-Xia Yi, Andries Kalsbeek, Andries Kalsbeek, Andries Kalsbeek
Published 2019-08-01

Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism

by Xiao-Lan Wang, Xiao-Lan Wang, Xiao-Lan Wang, Samantha E. C. Wolff, Samantha E. C. Wolff, Nikita Korpel, Nikita Korpel, Nikita Korpel, Irina Milanova, Irina Milanova, Cristina Sandu, Patrick C. N. Rensen, Sander Kooijman, Jean-Christophe Cassel, Jean-Christophe Cassel, Andries Kalsbeek, Andries Kalsbeek, Andries Kalsbeek, Anne-Laurence Boutillier, Anne-Laurence Boutillier, Chun-Xia Yi, Chun-Xia Yi, Chun-Xia Yi
Published 2020-12-01

The Main Molecular Mechanisms Underlying Methamphetamine- Induced Neurotoxicity and Implications for Pharmacological Treatment

by Xue Yang, Yong Wang, Qiyan Li, Yaxian Zhong, Liangpei Chen, Yajun Du, Jing He, Lvshuang Liao, Kun Xiong, Chun-xia Yi, Jie Yan
Published 2018-06-01

Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase

by Yuanqing Gao, Andrés Vidal-Itriago, Irina Milanova, Nikita L. Korpel, Martin J. Kalsbeek, Robby Zachariah Tom, Andries Kalsbeek, Susanna M. Hofmann, Chun-Xia Yi
Published 2018-01-01

Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5.

by Juliane Dinter, Jessica Mühlhaus, Carolin Leonie Wienchol, Chun-Xia Yi, Daniela Nürnberg, Silke Morin, Annette Grüters, Josef Köhrle, Torsten Schöneberg, Matthias Tschöp, Heiko Krude, Gunnar Kleinau, Heike Biebermann
Published 2015-01-01

Analysis of Human TAAR8 and Murine Taar8b Mediated Signaling Pathways and Expression Profile

by Jessica Mühlhaus, Juliane Dinter, Daniela Nürnberg, Maren Rehders, Maren Depke, Janine Golchert, Georg Homuth, Chun-Xia Yi, Silke Morin, Josef Köhrle, Klaudia Brix, Matthias Tschöp, Gunnar Kleinau, Heike Biebermann
Published 2014-11-01

The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia

by Martin J.T. Kalsbeek, Samantha E.C. Wolff, Nikita L. Korpel, Susanne E. la Fleur, Johannes A. Romijn, Eric Fliers, Andries Kalsbeek, Dick F. Swaab, Inge Huitinga, Elly M. Hol, Chun-Xia Yi
Published 2020-08-01

Circulating HDL levels control hypothalamic astrogliosis via apoA-I

by Anna Götz, Maarit Lehti, Elizabeth Donelan, Cynthia Striese, Sebastian Cucuruz, Stephan Sachs, Chun-Xia Yi, Stephen C. Woods, Samuel D. Wright, Timo D. Müller, Matthias H. Tschöp, Yuanqing Gao, Susanna M. Hofmann
Published 2018-09-01

Ring finger protein 11 inhibits melanocortin 3 and 4 receptor signaling

by Anne Müller, Lars Niederstadt, Wenke Jonas, Wenke Jonas, Chun-Xia Yi, Franziska Meyer, Petra Wiedmer, Jana Fischer, Carsten Grötzinger, Annette Schürmann, Annette Schürmann, Matthias Tschöp, Matthias Tschöp, Gunnar Kleinau, Annette Grüters, Heiko Krude, Heike Biebermann
Published 2016-08-01

Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner

by Irina V. Milanova, Irina V. Milanova, Martin J. T. Kalsbeek, Martin J. T. Kalsbeek, Xiao-Lan Wang, Xiao-Lan Wang, Nikita L. Korpel, Nikita L. Korpel, Dirk Jan Stenvers, Dirk Jan Stenvers, Samantha E. C. Wolff, Samantha E. C. Wolff, Paul de Goede, Paul de Goede, Annemieke C. Heijboer, Annemieke C. Heijboer, Eric Fliers, Eric Fliers, Susanne E. la Fleur, Susanne E. la Fleur, Susanne E. la Fleur, Andries Kalsbeek, Andries Kalsbeek, Andries Kalsbeek, Chun-Xia Yi, Chun-Xia Yi
Published 2019-06-01

TNFα drives mitochondrial stress in POMC neurons in obesity

by Chun-Xia Yi, Marc Walter, Yuanqing Gao, Soledad Pitra, Beata Legutko, Stefanie Kälin, Clarita Layritz, Cristina García-Cáceres, Maximilian Bielohuby, Martin Bidlingmaier, Stephen C. Woods, Alexander Ghanem, Karl-Klaus Conzelmann, Javier E. Stern, Martin Jastroch, Matthias H. Tschöp
Published 2017-05-01

Hypothalamic PGC-1α Protects Against High-Fat Diet Exposure by Regulating ERα

by Eugenia Morselli, Esther Fuente-Martin, Brian Finan, Min Kim, Aaron Frank, Cristina Garcia-Caceres, Carlos Rodriguez Navas, Ruth Gordillo, Michael Neinast, Sarada P. Kalainayakan, Dan L. Li, Yuanqing Gao, Chun-Xia Yi, Lisa Hahner, Biff F. Palmer, Matthias H. Tschöp, Deborah J. Clegg
Published 2014-10-01

Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity

by Yuanqing Gao, Andrés Vidal-Itriago, Martin J. Kalsbeek, Clarita Layritz, Cristina García-Cáceres, Robby Zachariah Tom, Thomas O. Eichmann, Frédéric M. Vaz, Riekelt H. Houtkooper, Nicole van der Wel, Arthur J. Verhoeven, Jie Yan, Andries Kalsbeek, Robert H. Eckel, Susanna M. Hofmann, Chun-Xia Yi
Published 2017-09-01

Dietary sugars, not lipids, drive hypothalamic inflammation

by Yuanqing Gao, Maximilian Bielohuby, Thomas Fleming, Gernot F. Grabner, Ewout Foppen, Wagner Bernhard, Mara Guzmán-Ruiz, Clarita Layritz, Beata Legutko, Erwin Zinser, Cristina García-Cáceres, Ruud M. Buijs, Stephen C. Woods, Andries Kalsbeek, Randy J. Seeley, Peter P. Nawroth, Martin Bidlingmaier, Matthias H. Tschöp, Chun-Xia Yi
Published 2017-08-01

The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction.

by Chun-Xia Yi, Kristy M Heppner, Henriette Kirchner, Jenny Tong, Maximillian Bielohuby, Bruce D Gaylinn, Timo D Müller, Erin Bartley, Harold W Davis, Yongmei Zhao, Anupama Joseph, Traci Kruthaupt, Nickki Ottaway, Dhiraj Kabra, Kirk M Habegger, Stephen C Benoit, Martin Bidlingmaier, Michael O Thorner, Diego Perez-Tilve, Matthias H Tschöp, Paul T Pfluger
Published 2012-01-01

Low-Fat Diet With Caloric Restriction Reduces White Matter Microglia Activation During Aging

by Zhuoran Yin, Zhuoran Yin, Divya D. Raj, Wandert Schaafsma, Roel A. van der Heijden, Susanne M. Kooistra, Aaffien C. Reijne, Aaffien C. Reijne, Aaffien C. Reijne, Xiaoming Zhang, Jill Moser, Nieske Brouwer, Peter Heeringa, Chun-Xia Yi, Gertjan van Dijk, Gertjan van Dijk, Gertjan van Dijk, Jon D. Laman, Erik W. G. M. Boddeke, Bart J. L. Eggen
Published 2018-03-01