Asymmetric aldol reactions and phenylthio migrations in synthesis

by Chibale, Kelly
Published 1992

How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?

by Chibale Kelly, Guantai Eric
Published 2011-03-01

CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives

by Doerig Christian, Vial Henri, Taramelli Donatella, Lanzer Michael, Bathurst Ian, Nwaka Solomon, Boulton Ian C, Chibale Kelly, Ward Steve A
Published 2010-07-01

Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles

by Mayoka, Godfrey Wabwile
Published 2019

Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum

by October, Natasha
Published 2014

Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.

by Pillay, Pamisha
Published 2014

Small molecule inhibitors of parasitic enzymes

by Chipeleme, Alex
Published 2014

Integration of In Silico and In Vitro ADMET properties in lead identification and optimization of compounds for the treatment of parasitic diseases

by Thelingwani, Roslyn
Published 2014

Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles

by Chisanga, Kelly
Published 2020

Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery

by Kigondu, Elizabeth Victoria Mumbi
Published 2016

Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents

by Omollo, Charles
Published 2017

A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria

by Kaur, Gurminder
Published 2017

The application of the Multi-Component Reaction (MCR) strategy in the design and synthesis of new antiplasmodial and antimycobacterial agents

by Tukulula, Matshawandile
Published 2015

Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues

by Ongarora, Dennis Sure Bagwasi
Published 2014

In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid

by Njoroge, Mathew
Published 2015

Antimycobacterial 2-aminoquinazolinones and benzoxazole-based oximes: synthesis, biological evaluation, physicochemical profiling and supramolecular derivatization

by Njaria, Paul Magutu
Published 2018

Design, synthesis and biological evaluation of verapamil analogues, reversed isoniazids and hybrid efflux pump inhibitors against Mycobacterium tuberculosis

by Kumar, Malkeet
Published 2016

Synthesis of activity-based protein profiling probes for malaria and hypertension disease models & potential novel ACE inhibitors with an attenuated zinc binding group

by Kambafwile, Henry Kunda
Published 2015

Curcumin-related hybrid compounds as potential antimalarial agents : design, synthesis, mechanistic investigations, biological evaluation and pharmacokinetic studies

by Guantai, Eric
Published 2014

Antimalarial imidazopyridazines and aminopyrazines: synthesis, physicochemical optimization and structure-activity relationships

by Cheuka, Peter Mubanga
Published 2019