Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex

by Caleb R. Glassman, Heather L. Parrish, Mark S. Lee, Michael S. Kuhns
Published 2018-01-01

Correction: A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization.

by Heather L Parrish, Caleb R Glassman, Madeline M Keenen, Neha R Deshpande, Matthew P Bronnimann, Michael S Kuhns
Published 2016-01-01

A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization.

by Heather L Parrish, Caleb R Glassman, Madeline M Keenen, Neha R Deshpande, Matthew P Bronnimann, Michael S Kuhns
Published 2015-01-01

Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

by Ricardo A Fernandes, Chaoran Li, Gang Wang, Xinbo Yang, Christina S Savvides, Caleb R Glassman, Shen Dong, Eric Luxenberg, Leah V Sibener, Michael E Birnbaum, Christophe Benoist, Diane Mathis, K Christopher Garcia
Published 2020-08-01

Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

by Caleb R Glassman, Leon Su, Sonia S Majri-Morrison, Hauke Winkelmann, Fei Mo, Peng Li, Magdiel Pérez-Cruz, Peggy P Ho, Ievgen Koliesnik, Nadine Nagy, Tereza Hnizdilova, Lora K Picton, Marek Kovar, Paul Bollyky, Lawrence Steinman, Everett Meyer, Jacob Piehler, Warren J Leonard, K Christopher Garcia
Published 2021-05-01