New Roles for Vitamin D Superagonists: From COVID to Cancer

by David J. Easty, Christine J. Farr, Bryan T. Hennessy, Bryan T. Hennessy
Published 2021-03-01

Obesity Correlation with Metastases Development and Response to First-Line Metastatic Chemotherapy in Breast Cancer

by Mohammed A. Osman, Bryan T. Hennessy
Published 2015-01-01

Obesity Correlation With Metastases Development and Response to First-Line Metastatic Chemotherapy in Breast Cancer

by Mohammed A. Osman, Bryan T. Hennessy
Published 2015-11-01

Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gen...

by Damien Kaukonen, Riina Kaukonen, Lélia Polit, Bryan T. Hennessy, Riikka Lund, Stephen F. Madden
Published 2020-07-01

Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro

by Ozlem Aslan, Mattia Cremona, Clare Morgan, Lydia W. Cheung, Gordon B. Mills, Bryan T. Hennessy
Published 2018-02-01

One year of procarbazine lomustine and vincristine is poorly tolerated in low grade glioma: a real world experience in a national neuro-oncology centre

by Rachel J. Keogh, Razia Aslam, Maeve A. Hennessy, Zac Coyne, Bryan T. Hennessy, Oscar S. Breathnach, Liam Grogan, Patrick G. Morris
Published 2021-02-01

Targeting the Epidermal Growth Factor Receptor in Epithelial Ovarian Cancer: Current Knowledge and Future Challenges

by Doris R. Siwak, Mark Carey, Bryan T. Hennessy, Catherine T. Nguyen, Mollianne J. McGahren Murray, Laura Nolden, Gordon B. Mills
Published 2010-01-01

Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors

by Constantin Jotzu, Eckhard Alt, Gabriel Welte, Jie Li, Bryan T. Hennessy, Eswaran Devarajan, Srinivasalu Krishnappa, Severin Pinilla, Lilly Droll, Yao-Hua Song
Published 2010-01-01

14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.

by Dashnamoorthy Ravi, Yidong Chen, Bijal Karia, Adam Brown, Ting Ting Gu, Jie Li, Mark S Carey, Bryan T Hennessy, Alexander J R Bishop
Published 2011-01-01

Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers

by Malgorzata Milewska, Mattia Cremona, Clare Morgan, John O’Shea, Aoife Carr, Sri HariKrishna Vellanki, Ann M. Hopkins, Sinead Toomey, Stephen F. Madden, Bryan T. Hennessy, Alex J. Eustace
Published 2018-01-01

Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis.

by Mandi M Murph, Wenbin Liu, Shuangxing Yu, Yiling Lu, Hassan Hall, Bryan T Hennessy, John Lahad, Marci Schaner, Aslaug Helland, Gunnar Kristensen, Anne-Lise Børresen-Dale, Gordon B Mills
Published 2009-01-01

Tumour Genome Characterization of a Rare Case of Pulmonary Enteric Adenocarcinoma and Prior Colon Adenocarcinoma

by Robert J. Smyth, Valentina Thomas, Joanna Fay, Ronan Ryan, Siobhan Nicholson, Ross K. Morgan, Liam Grogan, Oscar Breathnach, Patrick G. Morris, Sinead Toomey, Bryan T. Hennessy, Simon J. Furney
Published 2021-08-01

S100β as a serum marker in endocrine resistant breast cancer

by Sara Charmsaz, Éamon Hughes, Fiona T. Bane, Paul Tibbitts, Marie McIlroy, Christopher Byrne, Sinéad Cocchiglia, Jean McBryan, Bryan T. Hennessy, Róisín M. Dwyer, Michael J. Kerin, Arnold D. Hill, Leonie S. Young
Published 2017-04-01

Similar overall survival with reduced vs. standard dose bevacizumab monotherapy in progressive glioblastoma

by Jack Patrick Gleeson, Fergus Keane, Niamh M. Keegan, Emin Mammadov, Emily Harrold, Abdullah Alhusaini, Jeffrey Harte, Austin Eakin‐Love, Philip J. O'Halloran, Stephen MacNally, Bryan T. Hennessy, Oscar S. Breathnach, Liam Grogan, Patrick G. Morris
Published 2020-01-01

Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

by Alexandra Canonici, Alacoque L. Browne, Mohamed F. K. Ibrahim, Kevin P. Fanning, Sandra Roche, Neil T. Conlon, Fiona O’Neill, Justine Meiller, Mattia Cremona, Clare Morgan, Bryan T. Hennessy, Alex J. Eustace, Flavio Solca, Norma O’Donovan, John Crown
Published 2020-01-01

Prevalence of tumor BRCA1 and BRCA2 dysfunction in unselected patients with ovarian cancer

by Roshni D. Kalachand, Ciaran O’Riain, Sinead Toomey, Aoife Carr, Kirsten M. Timms, Sharon O’Toole, Stephen Madden, Mark Bates, John J. O’Leary, Noreen Gleeson, Dearbhaile O’Donnell, Liam Grogan, Oscar Breathnach, Angela Farrelly, Britta Stordal, Bryan T. Hennessy
Published 2020-09-01

Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer

by M. Janusz Mezynski, Angela M. Farrelly, Mattia Cremona, Aoife Carr, Clare Morgan, Julie Workman, Paul Armstrong, Jennifer McAuley, Stephen Madden, Joanna Fay, Katherine M. Sheehan, Elaine W. Kay, Ciara Holohan, Yasir Elamin, Shereen Rafee, Patrick G. Morris, Oscar Breathnach, Liam Grogan, Bryan T. Hennessy, Sinead Toomey
Published 2021-05-01

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted ther...

by Sinead Toomey, Alexander J. Eustace, Joanna Fay, Katherine M. Sheehan, Aoife Carr, Malgorzata Milewska, Stephen F. Madden, Ausra Teiserskiene, Elaine W. Kay, Norma O’Donovan, William Gallagher, Liam Grogan, Oscar Breathnach, Janice Walshe, Catherine Kelly, Brian Moulton, M. John Kennedy, Guiseppe Gullo, Arnold D. Hill, Colm Power, Deirdre Duke, Niamh Hambly, John Crown, Bryan T. Hennessy
Published 2017-07-01

Phase Ib Trial of Copanlisib, A Phosphoinositide-3 Kinase (PI3K) Inhibitor, with Trastuzumab in Advanced Pre-Treated HER2-Positive Breast Cancer “PantHER”

by Niamh M. Keegan, Simon J. Furney, Janice M. Walshe, Giuseppe Gullo, M. John Kennedy, Diarmuid Smith, John McCaffrey, Catherine M. Kelly, Keith Egan, Jennifer Kerr, Mark Given, Peter O’Donovan, Andres Hernando, Ausra Teiserskiene, Imelda Parker, Elaine Kay, Angela Farrelly, Aoife Carr, Giulio Calzaferri, Ray McDermott, Maccon M. Keane, Liam Grogan, Oscar Breathnach, Patrick G. Morris, Sinead Toomey, Bryan T. Hennessy
Published 2021-03-01

Genomic and Transcriptomic Characterisation of Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

by Sinead Toomey, Jillian Gunther, Aoife Carr, David C. Weksberg, Valentina Thomas, Manuela Salvucci, Orna Bacon, El-Masry Sherif, Joanna Fay, Elaine W. Kay, Katherine M. Sheehan, Deborah A. McNamara, Keith L Sanders, Geena Mathew, Oscar S. Breathnach, Liam Grogan, Patrick G. Morris, Wai C. Foo, Yi-Qian N. You, Jochen H. Prehn, Brian O’Neill, Sunil Krishnan, Bryan T. Hennessy, Simon J. Furney
Published 2020-07-01