Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method

by Kathryn S. Patton, M. Travis Harrison, Brian R. Long, Kelly Lau, Jennifer Holcomb, Rachel Owen, Theresa Kasprzyk, Sylvia Janetzki, Stephen J. Zoog, Christian Vettermann
Published 2021-09-01

Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment

by Eliver Eid Bou Ghosn, Jeffrey Waters, Megan Phillips, Ryo Yamamoto, Brian R. Long, Yang Yang, Rachel Gerstein, Cheryl A. Stoddart, Hiromitsu Nakauchi, Leonore A. Herzenberg
Published 2016-01-01

The Impact of Pre-existing Immunity on the Non-clinical Pharmacodynamics of AAV5-Based Gene Therapy

by Brian R. Long, Krystal Sandza, Jennifer Holcomb, Lucy Crockett, Gregory M. Hayes, Jeremy Arens, Carlos Fonck, Laurie S. Tsuruda, Becky Schweighardt, Charles A. O’Neill, Stephen Zoog, Christian Vettermann
Published 2019-06-01

HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts.

by Jason D Barbour, Mariana M Sauer, Elizabeth R Sharp, Keith E Garrison, Brian R Long, Helena Tomiyama, Katia C Bassichetto, Solange M Oliveira, Maria C Abbate, Douglas F Nixon, Esper G Kallas
Published 2007-10-01