Herpes simplex virus 2 ICP0 mutant viruses are avirulent and immunogenic: implications for a genital herpes vaccine.

by William P Halford, Ringo Püschel, Brandon Rakowski
Published 2010-08-01

A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccine.

by William P Halford, Ringo Püschel, Edward Gershburg, Andrew Wilber, Svetlana Gershburg, Brandon Rakowski
Published 2011-03-01

ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 gene.

by Mingyu Liu, Brandon Rakowski, Edward Gershburg, Carla M Weisend, Olivier Lucas, Edward E Schmidt, William P Halford
Published 2010-01-01