Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin

by Dennis S. Metselaar, Michaël H. Meel, Bente Benedict, Piotr Waranecki, Jan Koster, Gertjan J.L. Kaspers, Esther Hulleman
Published 2019-12-01

Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells

by Bente Benedict, Tanja van Harn, Marleen Dekker, Simone Hermsen, Asli Kucukosmanoglu, Wietske Pieters, Elly Delzenne-Goette, Josephine C Dorsman, Eva Petermann, Floris Foijer, Hein te Riele
Published 2018-10-01