Antibody modulation: Limiting the efficacy of therapeutic antibodies

by Vaughan, Andrew T., Cragg, Mark, Beers, Stephen A.
Published 2015

Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection

by Beers, Stephen A., French, Ruth R., Chan, Claude H.T, Lim, Sean H., Jarrett, Timothy C., Mora Vidal, Regina, Wijayaweera, Sahan S., Dixon, Sandra V., Kim, Hyung J., Cox, Kerry L., Kerr, Jonathan P., Johnston, David A., Johnson, Peter W.M, Verbeek, Sjef, Glennie, Martin J., Cragg, Mark S.
Published 2010

Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies

by White, Ann L., Chan, H.T. Claude, French, Ruth R., Willoughby, Jane E., Mockridge, C. Ian, Roghanian, Ali, Penfold, Christine A., Booth, Steven G., Dodhy, Ali, Polak, Marta E., Potter, Elizabeth A., Ardern-Jones, Michael R., Verbeek, J. Sjef, Johnson, Peter W.M, Al-Shamkhani, Aymen, Cragg, Mark S., Beers, Stephen A., Glennie, Martin J.
Published 2015

Antagonistic human FcyRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo

by Roghanian, Ali, Teige, Ingrid, Mårtensson, Linda, Cox, Kerry L., Kovacek, Mathilda, Ljungars, Anne, Mattson, Jenny, Sundberg, Annika, Vaughan, Andrew T., Shah, Vallari, Smyth, Neil R., Sheth, Bhavwanti, Chan, H.T. Claude, Li, Zhan-Chun, Williams, Emily L., Manfredi, Giusi, Oldham, Robert J., Mockridge, C. Ian, James, Sonya A., Dahal, Lekh N., Hussain, Khiyam, Nilsson, Björn, Verbeek, J. Sjef, Juliusson, Gunnar, Hansson, Markus, Jerkeman, Mats, Johnson, Peter W.M, Davies, Andrew, Beers, Stephen A., Glennie, Martin J., Frendéus, Björn, Cragg, Mark S.
Published 2015