IFNγ-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4+ T Cell Migration

by Nicholas A. Scott, Nicholas A. Scott, Yuxing Zhao, Balasubramanian Krishnamurthy, Balasubramanian Krishnamurthy, Stuart I. Mannering, Stuart I. Mannering, Thomas W. H. Kay, Thomas W. H. Kay, Helen E. Thomas, Helen E. Thomas
Published 2018-11-01

Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice

by Gaurang Jhala, Gaurang Jhala, Claudia Selck, Jonathan Chee, Jonathan Chee, Chun-Ting J. Kwong, Evan G. Pappas, Helen E. Thomas, Helen E. Thomas, Thomas W.H. Kay, Thomas W.H. Kay, Balasubramanian Krishnamurthy, Balasubramanian Krishnamurthy
Published 2021-03-01

The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice

by Tingting Ge, Tingting Ge, Gaurang Jhala, Stacey Fynch, Satoru Akazawa, Sara Litwak, Evan G. Pappas, Tara Catterall, Ishan Vakil, Ishan Vakil, Andrew J. Long, Lisa M. Olson, Balasubramanian Krishnamurthy, Balasubramanian Krishnamurthy, Thomas W. Kay, Thomas W. Kay, Helen E. Thomas, Helen E. Thomas
Published 2020-12-01

Granzyme B is dispensable in the development of diabetes in non-obese diabetic mice.

by Zia U Mollah, Kate L Graham, Balasubramanian Krishnamurthy, Prerak Trivedi, Thomas C Brodnicki, Joseph A Trapani, Thomas W Kay, Helen E Thomas
Published 2012-01-01