Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy

by Axel H. Schönthal
Published 2012-01-01

Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development

by Thomas C. Chen, Clovis O. da Fonseca, Axel H. Schönthal
Published 2018-12-01

Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases

by Thomas C. Chen, Clovis O. Da Fonseca, Axel H. Schönthal
Published 2016-09-01

Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treat...

by Thomas C. Chen, Nymph Chan, Radu O. Minea, Hannah Hartman, Florence M. Hofman, Axel H. Schönthal
Published 2018-09-01

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

by Thomas C. Chen, Nymph Chan, Shirin Labib, Jiali Yu, Hee-Yeon Cho, Florence M. Hofman, Axel H. Schönthal
Published 2018-01-01

Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia

by Axel H. Schönthal, Steve Swenson, Radu O. Minea, Hye Na Kim, Heeyeon Cho, Nazleen Mohseni, Yong-Mi Kim, Thomas C. Chen
Published 2021-07-01

Cytotoxic impact of a perillyl alcohol–temozolomide conjugate, NEO212, on cutaneous T-cell lymphoma

by Catalina Silva-Hirschberg, Hannah Hartman, Samantha Stack, Steve Swenson, Radu O. Minea, Michael A. Davitz, Thomas C. Chen, Axel H. Schönthal
Published 2019-12-01

Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.

by Simmy Thomas, Natasha Sharma, Reyna Gonzalez, Peng-Wen Pao, Florence M Hofman, Thomas C Chen, Stan G Louie, Michael C Pirrung, Axel H Schönthal
Published 2013-01-01

Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.

by Radu O Minea, Tuan Cao Duc, Stephen D Swenson, Hee-Yeon Cho, Mickey Huang, Hannah Hartman, Florence M Hofman, Axel H Schönthal, Thomas C Chen
Published 2020-01-01

Patient with Recurrent Glioblastoma Responding Favorably to Ketogenic Diet Combined with Intranasal Delivery of Perillyl Alcohol: A Case Report and Literature Review

by Juliana Guimarães Santos, Wanise Maria Souza Da Cruz, Axel H. Schönthal, Marcela D'alincourt Salazar, Cristina Asvolinsque Pantaleão Fontes, Thereza Quirico-Santos, Clovis Orlando da Fonseca
Published 2017-08-01