Cyclophosphamide treatment regulates the balance of functional/exhausted tumor-specific CD8+ T cells

by Aurélie Hanoteau, Coralie Henin, David Svec, Charlotte Bisilliat Donnet, Sébastien Denanglaire, Didier Colau, Pedro Romero, Oberdan Leo, Benoit Van den Eynde, Muriel Moser
Published 2017-08-01

TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiothe...

by Padmini Jayaraman, Falguni Parikh, Jared M. Newton, Aurelie Hanoteau, Charlotte Rivas, Rosemarie Krupar, Kimal Rajapakshe, Ravi Pathak, Kavin Kanthaswamy, Cassie MacLaren, Shixia Huang, Cristian Coarfa, Chad Spanos, Dean P. Edwards, Robin Parihar, Andrew G. Sikora
Published 2018-10-01

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition

by Jared M. Newton, Aurelie Hanoteau, Hsuan-Chen Liu, Angelina Gaspero, Falguni Parikh, Robyn D. Gartrell-Corrado, Thomas D. Hart, Damya Laoui, Jo A. Van Ginderachter, Neeraja Dharmaraj, William C. Spanos, Yvonne Saenger, Simon Young, Andrew G. Sikora
Published 2019-08-01

Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape

by Neeraja Dharmaraj, Stacey L. Piotrowski, Chen Huang, Jared M. Newton, Leonard S. Golfman, Aurelie Hanoteau, Sandeep T. Koshy, Aileen W. Li, Merlyn X. Pulikkathara, Bing Zhang, Jared K. Burks, David J. Mooney, Yu L. Lei, Andrew G. Sikora, Simon Young
Published 2019-04-01

Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy

by Aurelie Hanoteau, Jared M. Newton, Rosemarie Krupar, Chen Huang, Hsuan-Chen Liu, Angelina Gaspero, Robyn D. Gartrell, Yvonne M. Saenger, Thomas D. Hart, Saskia J. Santegoets, Damya Laoui, Chad Spanos, Falguni Parikh, Padmini Jayaraman, Bing Zhang, Sjoerd H. Van der Burg, Jo A. Van Ginderachter, Cornelis J. M. Melief, Andrew G. Sikora
Published 2019-01-01