Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue

by Carole L.C. Poon, Anthony M. Brumby, Helena E. Richardson
Published 2018-05-01

In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1–Rok–Myosin-II and JNK signalling

by Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M. Brumby, Helena E. Richardson
Published 2013-05-01

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

by Nezaket Turkel, Marta Portela, Carole Poon, Jason Li, Anthony M. Brumby, Helena E. Richardson
Published 2015-08-01

BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila.

by Karen Doggett, Nezaket Turkel, Lee F Willoughby, Jason Ellul, Michael J Murray, Helena E Richardson, Anthony M Brumby
Published 2015-01-01

An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

by Lee F. Willoughby, Tanja Schlosser, Samuel A. Manning, John P. Parisot, Ian P. Street, Helena E. Richardson, Patrick O. Humbert, Anthony M. Brumby
Published 2013-03-01

The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state.

by Nezaket Turkel, Virender K Sahota, Jessica E Bolden, Karen R Goulding, Karen Doggett, Lee F Willoughby, Enrique Blanco, Enrique Martin-Blanco, Montserrat Corominas, Jason Ellul, Toshiro Aigaki, Helena E Richardson, Anthony M Brumby
Published 2013-01-01