Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis

by Jean-Philippe Lanoix, Anne J. Lenaerts, Eric L. Nuermberger
Published 2015-06-01

Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment.

by Donald R Hoff, Gavin J Ryan, Emily R Driver, Cornelius C Ssemakulu, Mary A De Groote, Randall J Basaraba, Anne J Lenaerts
Published 2011-03-01

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

by Scott M. Irwin, Emily Driver, Edward Lyon, Christopher Schrupp, Gavin Ryan, Mercedes Gonzalez-Juarrero, Randall J. Basaraba, Eric L. Nuermberger, Anne J. Lenaerts
Published 2015-06-01

Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds.

by Garrett C Moraski, Nathalie Deboosère, Kate L Marshall, Heath A Weaver, Alexandre Vandeputte, Courtney Hastings, Lisa Woolhiser, Anne J Lenaerts, Priscille Brodin, Marvin J Miller
Published 2020-01-01

Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach.

by Gavin J Ryan, Donald R Hoff, Emily R Driver, Martin I Voskuil, Mercedes Gonzalez-Juarrero, Randall J Basaraba, Dean C Crick, John S Spencer, Anne J Lenaerts
Published 2010-06-01

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis.

by Rakesh, David F Bruhn, Michael S Scherman, Lisa K Woolhiser, Dora B Madhura, Marcus M Maddox, Aman P Singh, Robin B Lee, Julian G Hurdle, Michael R McNeil, Anne J Lenaerts, Bernd Meibohm, Richard E Lee
Published 2014-01-01

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

by Nicholas D. Walter, Sarah E. M. Born, Gregory T. Robertson, Matthew Reichlen, Christian Dide-Agossou, Victoria A. Ektnitphong, Karen Rossmassler, Michelle E. Ramey, Allison A. Bauman, Victor Ozols, Shelby C. Bearrows, Gary Schoolnik, Gregory Dolganov, Benjamin Garcia, Emmanuel Musisi, William Worodria, Laurence Huang, J. Lucian Davis, Nhung V. Nguyen, Hung V. Nguyen, Anh T. V. Nguyen, Ha Phan, Carol Wilusz, Brendan K. Podell, N’ Dira Sanoussi, Bouke C. de Jong, Corinne S. Merle, Dissou Affolabi, Helen McIlleron, Maria Garcia-Cremades, Ekaterina Maidji, Franceen Eshun-Wilson, Brandon Aguilar-Rodriguez, Dhuvarakesh Karthikeyan, Khisimuzi Mdluli, Cathy Bansbach, Anne J. Lenaerts, Radojka M. Savic, Payam Nahid, Joshua J. Vásquez, Martin I. Voskuil
Published 2021-05-01