rAAVrh74.MCK.GALGT2 Demonstrates Safety and Widespread Muscle Glycosylation after Intravenous Delivery in C57BL/6J Mice

by Deborah A. Zygmunt, Rui Xu, Ying Jia, Anna Ashbrook, Chelsea Menke, Guohong Shao, Jung Hae Yoon, Sonia Hamilton, Harshan Pisharath, Brad Bolon, Paul T. Martin
Published 2019-12-01

Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effec...

by Paul T Martin, Deborah A Zygmunt, Anna Ashbrook, Sonia Hamilton, Davin Packer, Sharla M Birch, Amanda K Bettis, Cynthia J Balog-Alvarez, Lee-Jae Guo, Peter P Nghiem, Joe N Kornegay
Published 2021-01-01