The NRF2-KEAP1 pathway is an early responsive gene network in arsenic exposed lymphoblastoid cells.

by Emilio J Córdova, Angélica Martínez-Hernández, Laura Uribe-Figueroa, Federico Centeno, Mirna Morales-Marín, Harsha Koneru, Matthew A Coleman, Lorena Orozco
Published 2014-01-01

Next-generation sequencing for identifying a novel/de novo pathogenic variant in a Mexican patient with cystic fibrosis: a case report

by Angélica Martínez-Hernández, Julieta Larrosa, Francisco Barajas-Olmos, Humberto García-Ortíz, Elvia C. Mendoza-Caamal, Cecilia Contreras-Cubas, Elaheh Mirzaeicheshmeh, José Luis Lezana, Lorena Orozco
Published 2019-05-01

Association of HMOX1 and NQO1 Polymorphisms with Metabolic Syndrome Components.

by Angélica Martínez-Hernández, Emilio J Córdova, Oscar Rosillo-Salazar, Humberto García-Ortíz, Cecilia Contreras-Cubas, Sergio Islas-Andrade, Cristina Revilla-Monsalve, Consuelo Salas-Labadía, Lorena Orozco
Published 2015-01-01

GSTT1 and GSTM1 null variants in Mestizo and Amerindian populations from northwestern Mexico and a literature review

by Luz Elena Palma-Cano, Emilio J. Córdova, Lorena Orozco, Angélica Martínez-Hernández, Miguel Cid, Irene Leal-Berumen, Angel Licón-Trillo, Ruth Lechuga-Valles, Mauricio González-Ponce, Everardo González-Rodríguez, Verónica Moreno-Brito
Published 2017-11-01

Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico

by Vanessa Gonzalez-Covarrubias, Marlet Morales-Franco, Omar F. Cruz-Correa, Angélica Martínez-Hernández, Humberto García-Ortíz, Francisco Barajas-Olmos, Alma Delia Genis-Mendoza, José Jaime Martínez-Magaña, Humberto Nicolini, Lorena Orozco, Xavier Soberón
Published 2019-10-01

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

by Francisco Barajas-Olmos, Federico Centeno-Cruz, Carlos Zerrweck, Iván Imaz-Rosshandler, Angélica Martínez-Hernández, Emilio J. Cordova, Claudia Rangel-Escareño, Faustino Gálvez, Armando Castillo, Hernán Maydón, Francisco Campos, Diana Gabriela Maldonado-Pintado, Lorena Orozco
Published 2018-02-01

Association between Vitamin D Deficiency and Single Nucleotide Polymorphisms in the Vitamin D Receptor and GC Genes and Analysis of Their Distribution in Mexican Postmenopausal Wom...

by Berenice Rivera-Paredez, Nayeli Macías, Mayeli M. Martínez-Aguilar, Alberto Hidalgo-Bravo, Mario Flores, Amado D. Quezada-Sánchez, Edgar Denova-Gutiérrez, Miguel Cid, Angelica Martínez-Hernández, Lorena Orozco, Manuel Quiterio, Yvonne N. Flores, Jorge Salmerón, Rafael Velázquez-Cruz
Published 2018-08-01

Two novel variants in DYRK1B causative of AOMS3: expanding the clinical spectrum

by Elvia C. Mendoza-Caamal, Francisco Barajas-Olmos, Elaheh Mirzaeicheshmeh, Ian Ilizaliturri-Flores, Carlos A. Aguilar-Salinas, Donaji V. Gómez-Velasco, Isabel Cicerón-Arellano, Adriana Reséndiz-Rodríguez, Angélica Martínez-Hernández, Cecilia Contreras-Cubas, Sergio Islas-Andrade, Carlos Zerrweck, Humberto García-Ortiz, Lorena Orozco
Published 2021-06-01

Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population.

by María Guadalupe Salas-Martínez, Yolanda Saldaña-Alvarez, Emilio J Cordova, Diana Karen Mendiola-Soto, Miguel A Cid-Soto, Angélica Luckie-Duque, Hermenegildo Vicenteño-Ayala, Francisco Barajas-Olmos, Cecilia Contreras-Cubas, Humberto García-Ortiz, Juan L Jiménez-Ruíz, Federico Centeno-Cruz, Angélica Martínez-Hernández, Elvia C Mendoza-Caamal, Elaheh Mirzaeicheshmeh, Lorena Orozco
Published 2019-01-01

Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico.

by Cecilia Contreras-Cubas, Beatríz E Sánchez-Hernández, Humberto García-Ortiz, Angélica Martínez-Hernández, Francisco Barajas-Olmos, Miguel Cid, Elvia C Mendoza-Caamal, Federico Centeno-Cruz, Gabriela Ortiz-Cruz, José Concepción Jiménez-López, Emilio J Córdova, Eva Gabriela Salas-Bautista, Yolanda Saldaña-Alvarez, Juan Carlos Fernández-López, Osvaldo M Mutchinick, Lorena Orozco
Published 2016-01-01

The L125F MATE1 variant enriched in populations of Amerindian origin is associated with increased plasma levels of metformin and lactate

by Monserrat I. Morales-Rivera, Radamés Alemón-Medina, Angélica Martínez-Hernández, Josefina Gómez-Garduño, Elaheh Mirzaeicheshmeh, Nelly F. Altamirano-Bustamante, Ian Ilizaliturri-Flores, Elvia C. Mendoza-Caamal, María G. Pérez-Guillé, Raquel García-Álvarez, Cecilia Contreras-Cubas, Federico Centeno-Cruz, Cristina Revilla-Monsalve, Humberto García-Ortiz, Francisco Barajas-Olmos, Lorena Orozco
Published 2021-10-01

Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study

by Elvia Cristina Mendoza-Caamal, Francisco Barajas-Olmos, Humberto García-Ortiz, Isabel Cicerón-Arellano, Angélica Martínez-Hernández, Emilio J. Córdova, Marcelino Esparza-Aguilar, Cecilia Contreras-Cubas, Federico Centeno-Cruz, Miguel Cid-Soto, Mirna Edith Morales-Marín, Adriana Reséndiz-Rodríguez, Juan Luis Jiménez-Ruiz, María Guadalupe Salas-Martínez, Yolanda Saldaña-Alvarez, Elaheh Mirzaeicheshmeh, María Rosalba Rojas-Martínez, Lorena Orozco
Published 2020-03-01

Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing

by Sandra Romero-Hidalgo, Adrián Ochoa-Leyva, Alejandro Garcíarrubio, Victor Acuña-Alonzo, Erika Antúnez-Argüelles, Martha Balcazar-Quintero, Rodrigo Barquera-Lozano, Alessandra Carnevale, Fernanda Cornejo-Granados, Juan Carlos Fernández-López, Rodrigo García-Herrera, Humberto García-Ortíz, Ángeles Granados-Silvestre, Julio Granados, Fernando Guerrero-Romero, Enrique Hernández-Lemus, Paola León-Mimila, Gastón Macín-Pérez, Angélica Martínez-Hernández, Marta Menjivar, Enrique Morett, Lorena Orozco, Guadalupe Ortíz-López, Fernando Pérez-Villatoro, Javier Rivera-Morales, Fernando Riveros-McKay, Marisela Villalobos-Comparán, Hugo Villamil-Ramírez, Teresa Villarreal-Molina, Samuel Canizales-Quinteros, Xavier Soberón
Published 2017-10-01

Deep Multi-OMICs and Multi-Tissue Characterization in a Pre- and Postprandial State in Human Volunteers: The GEMM Family Study Research Design

by Raul A. Bastarrachea, Hugo A. Laviada-Molina, Edna J. Nava-Gonzalez, Irene Leal-Berumen, Claudia Escudero-Lourdes, Fabiola Escalante-Araiza, Vanessa-Giselle Peschard, Rosa A. Veloz-Garza, Karin Haack, Angélica Martínez-Hernández, Francisco M. Barajas-Olmos, Fernanda Molina-Segui, Fatima A. Buenfil-Rello, Lucia Gonzalez-Ramirez, Reinhard Janssen-Aguilar, Ricardo Lopez-Muñoz, Fernanda Perez-Cetina, Janeth F. Gaytan-Saucedo, Zoila Vaquera, Judith Cornejo-Barrera, Juan Carlos Castillo-Pineda, Areli Murillo-Ramirez, Sara P. Diaz-Tena, Benigno Figueroa-Nuñez, Laura González-López, Rocío A. Salinas-Osornio, Melesio E. Valencia-Rendón, José Ángeles-Chimal, Jesús Santa-Olalla Tapia, José M. Remes-Troche, Salvador B. Valdovinos-Chavez, Eira E. Huerta-Avila, Xianlin Han, Lorena Orozco, Ernesto Rodriguez-Ayala, Susan Weintraub, Esther C. Gallegos-Cabrales, Shelley A. Cole, Jack W. Kent
Published 2018-11-01

Towards precision medicine: defining and characterizing adipose tissue dysfunction to identify early immunometabolic risk in symptom-free adults from the GEMM family study

by Ernesto Rodriguez-Ayala, Esther C. Gallegos-Cabrales, Laura Gonzalez-Lopez, Hugo A. Laviada-Molina, Rocio A. Salinas-Osornio, Edna J. Nava-Gonzalez, Irene Leal-Berumen, Claudia Escudero-Lourdes, Fabiola Escalante-Araiza, Fatima A. Buenfil-Rello, Vanessa-Giselle Peschard, Antonio Laviada-Nagel, Eliud Silva, Rosa A. Veloz-Garza, Angelica Martinez-Hernandez, Francisco M. Barajas-Olmos, Fernanda Molina-Segui, Lucia Gonzalez-Ramirez, Rebeca Espadas-Olivera, Ricardo Lopez-Muñoz, Ruy D. Arjona-Villicaña, Victor M. Hernandez-Escalante, Martha E. Rodriguez-Arellano, Janeth F. Gaytan-Saucedo, Zoila Vaquera, Monica Acebo-Martinez, Judith Cornejo-Barrera, Huertas-Quintero Jancy Andrea, Juan Carlos Castillo-Pineda, Areli Murillo-Ramirez, Sara P. Diaz-Tena, Benigno Figueroa-Nuñez, Melesio E. Valencia-Rendon, Rafael Garzon-Zamora, Juan Manuel Viveros-Paredes, José Ángeles-Chimal, Jesús Santa-Olalla Tapia, José M. Remes-Troche, Salvador B. Valdovinos-Chavez, Eira E. Huerta-Avila, Juan Carlos Lopez-Alvarenga, Anthony G Comuzzie, Karin Haack, Xianlin Han, Lorena Orozco, Susan Weintraub, Jack W. Kent, Shelley A. Cole, Raul A. Bastarrachea
Published 2020-01-01

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

by Julia K. Goodrich, Moriel Singer-Berk, Rachel Son, Abigail Sveden, Jordan Wood, Eleina England, Joanne B. Cole, Ben Weisburd, Nick Watts, Lizz Caulkins, Peter Dornbos, Ryan Koesterer, Zachary Zappala, Haichen Zhang, Kristin A. Maloney, Andy Dahl, Carlos A. Aguilar-Salinas, Gil Atzmon, Francisco Barajas-Olmos, Nir Barzilai, John Blangero, Eric Boerwinkle, Lori L. Bonnycastle, Erwin Bottinger, Donald W. Bowden, Federico Centeno-Cruz, John C. Chambers, Nathalie Chami, Edmund Chan, Juliana Chan, Ching-Yu Cheng, Yoon Shin Cho, Cecilia Contreras-Cubas, Emilio Córdova, Adolfo Correa, Ralph A. DeFronzo, Ravindranath Duggirala, Josée Dupuis, Ma Eugenia Garay-Sevilla, Humberto García-Ortiz, Christian Gieger, Benjamin Glaser, Clicerio González-Villalpando, Ma Elena Gonzalez, Niels Grarup, Leif Groop, Myron Gross, Christopher Haiman, Sohee Han, Craig L. Hanis, Torben Hansen, Nancy L. Heard-Costa, Brian E. Henderson, Juan Manuel Malacara Hernandez, Mi Yeong Hwang, Sergio Islas-Andrade, Marit E. Jørgensen, Hyun Min Kang, Bong-Jo Kim, Young Jin Kim, Heikki A. Koistinen, Jaspal Singh Kooner, Johanna Kuusisto, Soo-Heon Kwak, Markku Laakso, Leslie Lange, Jong-Young Lee, Juyoung Lee, Donna M. Lehman, Allan Linneberg, Jianjun Liu, Ruth J. F. Loos, Valeriya Lyssenko, Ronald C. W. Ma, Angélica Martínez-Hernández, James B. Meigs, Thomas Meitinger, Elvia Mendoza-Caamal, Karen L. Mohlke, Andrew D. Morris, Alanna C. Morrison, Maggie C. Y. Ng, Peter M. Nilsson, Christopher J. O’Donnell, Lorena Orozco, Colin N. A. Palmer, Kyong Soo Park, Wendy S. Post, Oluf Pedersen, Michael Preuss, Bruce M. Psaty, Alexander P. Reiner, Cristina Revilla-Monsalve, Stephen S. Rich, Jerome I. Rotter, Danish Saleheen, Claudia Schurmann, Xueling Sim, Rob Sladek, Kerrin S. Small, Wing Yee So, Timothy D. Spector, Konstantin Strauch, Tim M. Strom, E. Shyong Tai, Claudia H. T. Tam, Yik Ying Teo, Farook Thameem, Brian Tomlinson, Russell P. Tracy, Tiinamaija Tuomi, Jaakko Tuomilehto, Teresa Tusié-Luna, Rob M. van Dam, Ramachandran S. Vasan, James G. Wilson, Daniel R. Witte, Tien-Yin Wong, AMP-T2D-GENES Consortia, Noël P. Burtt, Noah Zaitlen, Mark I. McCarthy, Michael Boehnke, Toni I. Pollin, Jason Flannick, Josep M. Mercader, Anne O’Donnell-Luria, Samantha Baxter, Jose C. Florez, Daniel G. MacArthur, Miriam S. Udler
Published 2021-06-01