A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase1

by Hudson W. Coates, Andrew J. Brown
Published 2019-10-01

Lipid sensing tips the balance for a key cholesterol synthesis enzyme

by Ngee Kiat Chua, Andrew J. Brown
Published 2020-11-01

The shape of human squalene epoxidase expands the arsenal against cancer

by Andrew J. Brown, Ngee Kiat Chua, Nieng Yan
Published 2019-02-01

An Essential Role of Hrs/Vps27 in Endosomal Cholesterol Trafficking

by Ximing Du, Abdulla S. Kazim, Andrew J. Brown, Hongyuan Yang
Published 2012-01-01

DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme

by Eser J. Zerenturk, Laura J. Sharpe, Andrew J. Brown
Published 2014-03-01

A practical comparison of ligation-independent cloning techniques.

by Julian Stevenson, James R Krycer, Lisa Phan, Andrew J Brown
Published 2013-01-01

Rapid hepatic metabolism of 7-ketocholesterol in vivo: implications for dietary oxysterols

by Malcolm A. Lyons, Samir Samman, Lissa Gatto, Andrew J. Brown
Published 1999-10-01

The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally[S]

by Winnie Luu, Gene Hart-Smith, Laura J. Sharpe, Andrew J. Brown
Published 2015-04-01

The Adaptor Protein Alix is Involved in the Interaction Between the Ubiquitin Ligase NEDD4-1 and its Targets, ABCG1 and ABCG4

by Amjad Alrosan, Shereen M. Aleidi, Alryel Yang, Andrew J. Brown, Ingrid C. Gelissen
Published 2019-06-01

Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid

by Ingrid C. Gelissen, Kerry-Ann Rye, Andrew J. Brown, Roger T. Dean, Wendy Jessup
Published 1999-09-01

Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells: accumulation of oxidized esters in lysosomes

by Andrew J. Brown, Erin L. Mander, Ingrid C. Gelissen, Leonard Kritharides, Roger T. Dean, Wendy Jessup
Published 2000-02-01

Cryptic diversity among Yazoo Darters (Percidae: Etheostoma raneyi) in disjunct watersheds of northern Mississippi

by Ken A. Sterling, Stuart V. Nielsen, Andrew J. Brown, Melvin L. Warren, Jr., Brice P. Noonan
Published 2020-05-01

Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis[S]

by Winnie Luu, Eser J. Zerenturk, Ika Kristiana, Martin P. Bucknall, Laura J. Sharpe, Andrew J. Brown
Published 2014-03-01

Protein kinase A modulates the activity of a major human isoform of ABCG1

by Ingrid C. Gelissen, Laura J. Sharpe, Cecilia Sandoval, Geetha Rao, Maaike Kockx, Leonard Kritharides, Wendy Jessup, Andrew J. Brown
Published 2012-10-01

N‐Palmitoylglycine and other N‐acylamides activate the lipid receptor G2A/GPR132

by James R. Foster, Shohta Ueno, Mao Xiang Chen, Jenni Harvey, Simon J. Dowell, Andrew J. Irving, Andrew J. Brown
Published 2019-12-01

ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane

by Rajesh Ghai, Ximing Du, Huan Wang, Jiangqing Dong, Charles Ferguson, Andrew J. Brown, Robert G. Parton, Jia-Wei Wu, Hongyuan Yang
Published 2017-10-01

Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis[S]

by Weihua Fei, Hui Li, Guanghou Shui, Tamar S. Kapterian, Christopher Bielby, Ximing Du, Andrew J. Brown, Peng Li, Markus R. Wenk, Pingsheng Liu, Hongyuan Yang
Published 2011-12-01

Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2

by Jiangqing Dong, Ximing Du, Huan Wang, Jue Wang, Chang Lu, Xiang Chen, Zhiwen Zhu, Zhipu Luo, Li Yu, Andrew J. Brown, Hongyuan Yang, Jia-Wei Wu
Published 2019-02-01

A role for phosphatidic acid in the formation of "supersized" lipid droplets.

by Weihua Fei, Guanghou Shui, Yuxi Zhang, Natalie Krahmer, Charles Ferguson, Tamar S Kapterian, Ruby C Lin, Ian W Dawes, Andrew J Brown, Peng Li, Xun Huang, Robert G Parton, Markus R Wenk, Tobias C Walther, Hongyuan Yang
Published 2011-07-01

MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo‐allergic and anaphylactoid reactions

by Jak Grimes, Sapna Desai, Neil W. Charter, James Lodge, Rita Moita Santos, Albert Isidro‐Llobet, Andrew M. Mason, Zining Wu, Lawrence A. Wolfe III, Lakshmi Anantharaman, Andrew Green, Angela M. Bridges, Deidre A. Dalmas Wilk, Andrew J. Brown
Published 2019-12-01