ELK1 has a dual activating and repressive role in human embryonic stem cells [version 2; peer review: 2 approved]

by Ian Prise, Andrew D. Sharrocks
Published 2019-07-01

ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes.

by Zaneta Odrowaz, Andrew D Sharrocks
Published 2012-01-01

The ETS transcription factors ELK1 and GABPA regulate different gene networks to control MCF10A breast epithelial cell migration.

by Zaneta Odrowaz, Andrew D Sharrocks
Published 2012-01-01

RNF4 interacts with multiSUMOylated ETV4 [version 2; referees: 2 approved]

by Elisa Aguilar-Martinez, Baoqiang Guo, Andrew D. Sharrocks
Published 2017-02-01

The ubiquitin ligase UBE3A dampens ERK pathway signalling in HPV E6 transformed HeLa cells.

by Elisa Aguilar-Martinez, Claire Morrisroe, Andrew D Sharrocks
Published 2015-01-01

Protein kinase C coordinates histone H3 phosphorylation and acetylation

by Zoulfia Darieva, Aaron Webber, Stacey Warwood, Andrew D Sharrocks
Published 2015-10-01

Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes

by Hee-Jeong Im, Andrew D Sharrocks, Xia Lin, et al
Published 2009-10-01

Genome-wide Interrogation of Protein-DNA Interactions in Mammalian Cells Using ChIPmentation

by Wei Xu, Ying Ye, Andrew D. Sharrocks, Wensheng Zhang, Xi Chen
Published 2020-12-01

A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation.

by Shen-Hsi Yang, Tuzer Kalkan, Claire Morrisroe, Austin Smith, Andrew D Sharrocks
Published 2012-01-01

PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals [version 1; peer review: 2 approved]

by Peter Briggs, A. Louise Hunter, Shen-hsi Yang, Andrew D. Sharrocks, Mudassar Iqbal
Published 2021-07-01

Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma

by Connor Rogerson, Samuel Ogden, Edward Britton, The OCCAMS Consortium, Yeng Ang, Andrew D Sharrocks
Published 2020-09-01

EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas.

by Karol Nowicki-Osuch, Yaoyong Li, Mairi Challinor, David T Gerrard, Neil A Hanley, Andrew D Sharrocks
Published 2017-01-01

ZIC3 Controls the Transition from Naive to Primed Pluripotency

by Shen-Hsi Yang, Munazah Andrabi, Rebecca Biss, Syed Murtuza Baker, Mudassar Iqbal, Andrew D. Sharrocks
Published 2019-06-01

Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency

by Shen-Hsi Yang, Tüzer Kalkan, Claire Morissroe, Hendrik Marks, Hendrik Stunnenberg, Austin Smith, Andrew D. Sharrocks
Published 2014-06-01

A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity.

by Jacqueline C Merrill, Tiffany A Melhuish, Michael H Kagey, Shen-Hsi Yang, Andrew D Sharrocks, David Wotton
Published 2010-01-01

Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.

by Edward Britton, Connor Rogerson, Shaveta Mehta, Yaoyong Li, Xiaodun Li, OCCAMS consortium, Rebecca C Fitzgerald, Yeng S Ang, Andrew D Sharrocks
Published 2017-08-01

Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders

by Dave T. Gerrard, Andrew A. Berry, Rachel E. Jennings, Matthew J. Birket, Peyman Zarrineh, Myles G. Garstang, Sarah L. Withey, Patrick Short, Sandra Jiménez-Gancedo, Panos N. Firbas, Ian Donaldson, Andrew D. Sharrocks, Karen Piper Hanley, Matthew E. Hurles, José Luis Gomez-Skarmeta, Nicoletta Bobola, Neil A. Hanley
Published 2020-08-01