Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer’s Disease

by Hianara A. Bustamante, Hianara A. Bustamante, Alexis E. González, Alexis E. González, Cristobal Cerda-Troncoso, Ronan Shaughnessy, Ronan Shaughnessy, Carola Otth, Carola Otth, Andrea Soza, Andrea Soza, Patricia V. Burgos, Patricia V. Burgos, Patricia V. Burgos
Published 2018-05-01

The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesio...

by Cecilia Arriagada, Charlotte Luchsinger, Alexis E González, Tomás Schwenke, Gloria Arriagada, Hugo Folch, Pamela Ehrenfeld, Patricia V Burgos, Gonzalo A Mardones
Published 2019-01-01

GOLPH3 Regulates EGFR in T98G Glioblastoma Cells by Modulating Its Glycosylation and Ubiquitylation

by Cecilia Arriagada, Viviana A. Cavieres, Charlotte Luchsinger, Alexis E. González, Vanessa C. Muñoz, Jorge Cancino, Patricia V. Burgos, Gonzalo A. Mardones
Published 2020-11-01

The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport

by Hianara A Bustamante, Karina Cereceda, Alexis E González, Guillermo E Valenzuela, Yorka Cheuquemilla, Sergio Hernández, Eloisa Arias-Muñoz, Cristóbal Cerda-Troncoso, Susanne Bandau, Andrea Soza, Gudrun Kausel, Bredford Kerr, Gonzalo A Mardones, Jorge Cancino, Ronald T Hay, Alejandro Rojas-Fernandez, Patricia V Burgos
Published 2020-03-01