Dissecting conformational changes in APP's transmembrane domain linked to ε-efficiency in familial Alzheimer's disease.

by Alexander Götz, Christina Scharnagl
Published 2018-01-01

Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix

by Charlotte Spitz, Christine Schlosser, Nadja Guschtschin-Schmidt, Walter Stelzer, Simon Menig, Alexander Götz, Martina Haug-Kröper, Christina Scharnagl, Dieter Langosch, Claudia Muhle-Goll, Regina Fluhrer
Published 2020-12-01

A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.

by Sabine M Hölter, Mary Stromberg, Marina Kovalenko, Lillian Garrett, Lisa Glasl, Edith Lopez, Jolene Guide, Alexander Götz, Wolfgang Hans, Lore Becker, Birgit Rathkolb, Jan Rozman, Anja Schrewed, Martin Klingenspor, Thomas Klopstock, Holger Schulz, Eckhard Wolf, Wolfgang Wursta, Tammy Gillis, Hiroko Wakimoto, Jonathan Seidman, Marcy E MacDonald, Susan Cotman, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Jong-Min Lee, Vanessa C Wheeler
Published 2013-01-01