Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells.

by Lara Wohlbold, Karl A Merrick, Saurav De, Ramon Amat, Jun Hyun Kim, Stéphane Larochelle, Jasmina J Allen, Chao Zhang, Kevan M Shokat, John H J Petrini, Robert P Fisher
Published 2012-08-01

Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors

by Sampada Kalan, Ramon Amat, Miriam Merzel Schachter, Nicholas Kwiatkowski, Brian J. Abraham, Yanke Liang, Tinghu Zhang, Calla M. Olson, Stéphane Larochelle, Richard A. Young, Nathanael S. Gray, Robert P. Fisher
Published 2017-10-01