The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

by Li Pui-Kai, Schwartz Eric B, Li Chenglong, Lin Jiayuh, Bear Misty D, Fossey Stacey L, Fuchs James R, Fenger Joelle, Kisseberth William C, London Cheryl A
Published 2011-03-01

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

by Lin Li, Deangelis Stephanie, Foust Elizabeth, Fuchs James, Li Chenglong, Li Pui-Kai, Schwartz Eric B, Lesinski Gregory B, Benson Don, Lü Jiagao, Hoyt Dale, Lin Jiayuh
Published 2010-08-01

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

by Young Gregory S, Fossey Stacey L, Hoyt Dale G, Lin Jiayuh, Abdelhamid Dalia, Schwartz Eric B, Benson Don M, Bakan Courtney, Yui Jennifer, Li Chenglong, Fuchs James R, Bill Matthew A, Carson William E, Li Pui-Kai, Lesinski Gregory B
Published 2010-06-01