NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease

by Randilea D. Nichols, Jakob von Moltke, Russell E. Vance
Published 2017-12-01

Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.

by Augusto V Gonçalves, Shally R Margolis, Gustavo F S Quirino, Danielle P A Mascarenhas, Isabella Rauch, Randilea D Nichols, Eduard Ansaldo, Mary F Fontana, Russell E Vance, Dario S Zamboni
Published 2019-06-01