P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion

by Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Vanessa Figliuolo, Claudia Lucia Martins Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva
Published 2020-01-01

Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to L. amazonensis control mediated by P2X7 receptor and leukotriene B4.

by Mariana M Chaves, Debora A Sinflorio, Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Aline Cristina Abreu Moreira-Souza, Thuany Prado Rangel, Claudia L M Silva, Maria Bellio, Claudio Canetti, Robson Coutinho-Silva
Published 2019-06-01